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    med31 mediator complex subunit Med31 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539504, updated on 22-Jun-2024

    Summary

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    Gene symbol
    med31
    Gene description
    mediator complex subunit Med31
    Locus tag
    SPOM_SPCP31B10.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    sep10; soh1
    Old locus tag
    SPCP31B10.03c
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    Genomic context

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    See med31 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (525859..526748, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene DNAJ domain protein Cwf23 Neighboring gene ncRNA Neighboring gene protein psg2 Neighboring gene ncRNA Neighboring gene tyrosyl-DNA phosphodiesterase Tdp1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic expression patterns in cell separation mutants of Schizosaccharomyces pombe defective in the genes sep10 ( + ) and sep15 ( + ) coding for the Mediator subunits Med31 and Med8. Miklos I, et al. Mol Genet Genomics, 2008 Mar. PMID 17922236
    2. The Schizosaccharomyces pombe genes sep10 and sep11 encode putative general transcriptional regulators involved in multiple cellular processes. Szilagyi Z, et al. Mol Genet Genomics, 2002 Dec. PMID 12471453
    3. Impairment of the TFIIH-associated CDK-activating kinase selectively affects cell cycle-regulated gene expression in fission yeast. Lee KM, et al. Mol Biol Cell, 2005 Jun. PMID 15829570, Free PMC Article
    4. The Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator. Linder T, et al. J Biol Chem, 2004 Nov 19. PMID 15356001
    5. RNA interference is essential for cellular quiescence. Roche B, et al. Science, 2016 Nov 11. PMID 27738016, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Med8 and Med31 proteins act as coactivators of the Sep1-Ace2-dependent cell separation genes.
      Title: Genomic expression patterns in cell separation mutants of Schizosaccharomyces pombe defective in the genes sep10 ( + ) and sep15 ( + ) coding for the Mediator subunits Med31 and Med8.
    2. Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator
      Title: The Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med31

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      525859..526748 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022852.3 → NP_587859.1  mediator complex subunit Med31 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587859.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9USH1
      Conserved Domains (1) summary
      COG5088
      Location:1 → 114
      SOH1; Rad5p-binding protein [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    5N9J_R.1
    5U0P_3.1
    5U0S_3.1

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials