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    car2 ornithine transaminase Car2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540626, updated on 18-Sep-2024

    Summary

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    Official Symbol
    car2
    Official Full Name
    ornithine transaminase Car2
    Primary source
    PomBase:SPBC21C3.08c
    Locus tag
    SPOM_SPBC21C3.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See car2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3809059..3810849, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U2 snRNP-associated protein Sap62 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene tRNA (cytosine) methyltransferase Neighboring gene ncRNA Neighboring gene acylpyruvase Oaa1 Neighboring gene 5-amino-6-(5-phosphoribosylamino) uracil reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genetic engineering solution to the "arginine conversion problem" in stable isotope labeling by amino acids in cell culture (SILAC). Bicho CC, et al. Mol Cell Proteomics, 2010 Jul. PMID 20460254, Free PMC Article
    2. SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Singh NS, et al. Curr Biol, 2011 Dec 6. PMID 22119525, Free PMC Article
    3. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article
    4. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables identical protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ornithine aminotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pyridoxal phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-proline biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in arginine catabolic process to glutamate IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in arginine catabolic process to proline via ornithine IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in arginine catabolic process to proline via ornithine IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    ornithine transaminase Car2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3809059..3810849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022508.3 → NP_596588.1  ornithine transaminase Car2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596588.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78805, Q9P7L5
      Conserved Domains (2) summary
      COG0160
      Location:25 → 424
      GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]
      TIGR01885
      Location:13 → 422
      Orn_aminotrans; ornithine aminotransferase
    Nucleotide Protein
    Heading Accession and Version

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