U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    snf22 SWI/SNF ATP-dependent chromatin remodeler Snf22 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538881, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    snf22
    Official Full Name
    SWI/SNF ATP-dependent chromatin remodeler Snf22
    Primary source
    PomBase:SPCC1620.14c
    Locus tag
    SPOM_SPCC1620.14C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPCC830.01c
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See snf22 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (2171573..2178240, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphoglycerate mutase family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot. Yamada T, et al. EMBO J, 2004 Apr 21. PMID 14988732, Free PMC Article
    2. Interplay between chromatin modulators and histone acetylation regulates the formation of accessible chromatin in the upstream regulatory region of fission yeast fbp1. Adachi A, et al. Genes Genet Syst, 2018 May 3. PMID 28674280
    3. Distinct chromatin modulators regulate the formation of accessible and repressive chromatin at the fission yeast recombination hotspot ade6-M26. Hirota K, et al. Mol Biol Cell, 2008 Mar. PMID 18199689, Free PMC Article
    4. Schizosaccharomyces pombe centromere protein Mis19 links Mis16 and Mis18 to recruit CENP-A through interacting with NMD factors and the SWI/SNF complex. Hayashi T, et al. Genes Cells, 2014 Jul. PMID 24774534
    5. Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast. Monahan BJ, et al. Nat Struct Mol Biol, 2008 Aug. PMID 18622392, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.
      Title: Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.
    2. The Swi2/Snf2-like Snf22 is absolutely required for chromatin remodeling and meiotic recombination around the meiotic recombination hotspot M26. [snf22]
      Title: Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IC
    Inferred by Curator
    more info
    		  
    enables ATP hydrolysis activity IC
    Inferred by Curator
    more info
    		  
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleosome array spacer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic spindle HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    SWI/SNF ATP-dependent chromatin remodeler Snf22

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      2171573..2178240 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023463.3 → NP_588472.2  SWI/SNF ATP-dependent chromatin remodeler Snf22 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588472.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94421, Q9UU97
      Conserved Domains (10) summary
      cd05519
      Location:1518 → 1620
      Bromo_SNF2; Bromodomain, SNF2-like subfamily, specific to fungi. SNF2 is a yeast protein involved in transcriptional activation, it is the catalytic component of the SWI/SNF ATP-dependent chromatin remodeling complex. The protein is essential for the regulation of ...
      smart00951
      Location:428 → 463
      QLQ; QLQ is named after the conserved Gln, Leu, Gln motif
      COG0553
      Location:582 → 1345
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      COG5076
      Location:1395 → 1673
      COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
      cd00046
      Location:889 → 1028
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00271
      Location:1187 → 1301
      Helicase_C; Helicase conserved C-terminal domain
      pfam07529
      Location:711 → 775
      HSA; HSA
      pfam14618
      Location:229 → 292
      DUF4452; Domain of unknown function (DUF4452)
      pfam14619
      Location:1398 → 1463
      SnAC; Snf2-ATP coupling, chromatin remodelling complex
      pfam15273
      Location:216 → 396
      NHS; NHS-like
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials