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    FIGNL1 fidgetin like 1 [ Homo sapiens (human) ]

    Gene ID: 63979, updated on 30-Oct-2024

    Summary

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    Official Symbol
    FIGNL1provided by HGNC
    Official Full Name
    fidgetin like 1provided by HGNC
    Primary source
    HGNC:HGNC:13286
    See related
    Ensembl:ENSG00000132436 MIM:615383; AllianceGenome:HGNC:13286
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene encodes a member of the AAA ATPase family of proteins. The encoded protein is recruited to sites of DNA damage where it plays a role in DNA double-strand break repair via homologous recombination. This protein has also been shown to localize to the centrosome and inhibit ciliogenesis, and may regulate the proliferation and differentiation of osteoblasts. [provided by RefSeq, Oct 2016]
    Expression
    Ubiquitous expression in lymph node (RPKM 1.9), appendix (RPKM 1.8) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See FIGNL1 in Genome Data Viewer
    Location:
    7p12.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (50444133..50450350, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (50605348..50611565, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (50511831..50518048, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene IKAROS family zinc finger 1 Neighboring gene uncharacterized LOC124901631 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26004 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50477534-50478034 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26005 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26006 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26007 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:50488572-50489105 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:50514049-50515248 Neighboring gene RNA, U6 small nuclear 1091, pseudogene Neighboring gene Sharpr-MPRA regulatory region 9826 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18183 Neighboring gene VISTA enhancer hs2059 Neighboring gene H3K4me1 hESC enhancers GRCh37_chr7:50569579-50570080 and GRCh37_chr7:50570081-50570580 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50581285-50581919 Neighboring gene dopa decarboxylase Neighboring gene Neanderthal introgressed variant-containing enhancers experimental_99424 and experimental_99425 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr7:50598907-50600106 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr7:50602470-50603669 Neighboring gene DDC antisense RNA 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:50637965-50638490 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_99443 Neighboring gene growth factor receptor bound protein 10 Neighboring gene uncharacterized LOC124901632

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. FIGNL1 Promotes Hepatocellular Carcinoma Formation via Remodeling ECM-receptor Interaction Pathway Mediated by HMMR. Wang J, et al. Curr Gene Ther, 2024. PMID 37929733, Free PMC Article
    2. FIGNL1 promotes non‑small cell lung cancer cell proliferation. Li M, et al. Int J Oncol, 2021 Jan. PMID 33367932, Free PMC Article
    3. FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide. Ma J, et al. Oncol Rep, 2017 Apr. PMID 28260065, Free PMC Article
    4. FIGNL1 is a potential biomarker of cisplatin resistance in non-small cell lung cancer. Meng C, et al. Int J Biol Markers, 2022 Sep. PMID 35791674
    5. Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation. Matsuzaki K, et al. Nucleic Acids Res, 2024 Jun 10. PMID 38597669, Free PMC Article

    See all (50) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation.
      Title: Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation.
    2. FIGNL1 Promotes Hepatocellular Carcinoma Formation via Remodeling ECM-receptor Interaction Pathway Mediated by HMMR.
      Title: FIGNL1 Promotes Hepatocellular Carcinoma Formation via Remodeling ECM-receptor Interaction Pathway Mediated by HMMR.
    3. FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress.
      Title: FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress.
    4. FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination.
      Title: FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination.
    5. FIGNL1 is a potential biomarker of cisplatin resistance in non-small cell lung cancer.
      Title: FIGNL1 is a potential biomarker of cisplatin resistance in non-small cell lung cancer.
    6. FIGNL1 promotes nonsmall cell lung cancer cell proliferation.
      Title: FIGNL1 promotes non‑small cell lung cancer cell proliferation.
    7. The results identify Fignl1 as a key dynein regulator required for motor circuit wiring.
      Title: FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation.
    8. SWSAP1 protects RAD51 filaments by antagonizing the anti-recombinase, FIGNL1.
      Title: Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase.
    9. FIGL-1 is a new centrosomal protein and inhibits ciliogenesis.
      Title: Fidgetin-like 1 is a ciliogenesis-inhibitory centrosome protein.
    10. Further research assessing the functions and mechanisms of FIGNL1, and other homologous recombination pathway genes may disclose unique pathological characteristics of SCLC, and help identify potential therapeutic targets and biomarkers
      Title: FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide.
    Submit: New GeneRIF Correction See all GeneRIFs (12)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables magnesium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables microtubule severing ATPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ATP metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cellular response to ionizing radiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in male meiotic nuclear division ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in negative regulation of intrinsic apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in osteoblast differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in osteoblast proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of cell cycle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of double-strand break repair via homologous recombination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in extracellular exosome HDA PubMed 
    located_in nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    fidgetin-like protein 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_051949.1 RefSeqGene

      Range
      5057..11274
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001042762.5 → NP_001036227.1  fidgetin-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001036227.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Related
      ENSP00000349356.4, ENST00000356889.8
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    2. NM_001287492.4 → NP_001274421.1  fidgetin-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001274421.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) encodes the longer isoform (1). Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Related
      ENSP00000399997.1, ENST00000433017.6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    3. NM_001287493.3 → NP_001274422.1  fidgetin-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001274422.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Related
      ENSP00000483543.1, ENST00000615084.4
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    4. NM_001287494.4 → NP_001274423.1  fidgetin-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001274423.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    5. NM_001287495.3 → NP_001274424.1  fidgetin-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001274424.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Related
      ENSP00000483126.1, ENST00000617389.4
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    6. NM_001287496.4 → NP_001274425.1  fidgetin-like protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001274425.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and includes additional splice sites in the 5' coding region resulting in translation initiation from a downstream start codon, compared to variant 3. It encodes isoform 2, which is shorter at the N-terminus, compared to isoform 1. Variants 7-9 encode the same isoform (2).
      Source sequence(s)
      AC018705
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (3) summary
      smart00382
      Location:322 → 458
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:326 → 456
      AAA; ATPase family associated with various cellular activities (AAA)
      pfam09336
      Location:520 → 560
      Vps4_C; Vps4 C terminal oligomerization domain

    7. NM_001346558.3 → NP_001333487.1  fidgetin-like protein 1 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR and includes additional splice sites in the 5' coding region resulting in translation initiation from a downstream start codon, compared to variant 3. It encodes isoform 2, which is shorter at the N-terminus, compared to isoform 1. Variants 7-9 encode the same isoform (2).
      Source sequence(s)
      AC018705
      UniProtKB/TrEMBL
      B3KNH6

    8. NM_001346559.3 → NP_001333488.1  fidgetin-like protein 1 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR and includes additional splice sites in the 5' coding region resulting in translation initiation from a downstream start codon, compared to variant 3. It encodes isoform 2, which is shorter at the N-terminus, compared to isoform 1. Variants 7-9 encode the same isoform (2).
      Source sequence(s)
      AC018705
      UniProtKB/TrEMBL
      B3KNH6

    9. NM_001346560.3 → NP_001333489.1  fidgetin-like protein 1 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    10. NM_001346561.3 → NP_001333490.1  fidgetin-like protein 1 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    11. NM_001346562.3 → NP_001333491.1  fidgetin-like protein 1 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    12. NM_001346563.3 → NP_001333492.1  fidgetin-like protein 1 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    13. NM_001346564.3 → NP_001333493.1  fidgetin-like protein 1 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    14. NM_001346565.3 → NP_001333494.1  fidgetin-like protein 1 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    15. NM_022116.7 → NP_071399.2  fidgetin-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_071399.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. Variants 1-6 and 10-15 encode the same isoform (1).
      Source sequence(s)
      AC018705
      Consensus CDS
      CCDS5510.1
      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Related
      ENSP00000378924.2, ENST00000395556.6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      50444133..50450350 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024446865.2 → XP_024302633.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    2. XM_024446863.2 → XP_024302631.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    3. XM_024446864.2 → XP_024302632.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    4. XM_011515470.4 → XP_011513772.1  fidgetin-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011513772.1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    5. XM_047420693.1 → XP_047276649.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      Related
      ENSP00000410811.1, ENST00000419119.1

    6. XM_017012501.2 → XP_016867990.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
      UniProtKB/TrEMBL
      B3KNH6
      Conserved Domains (1) summary
      COG0464
      Location:374 → 668
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      50605348..50611565 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054358782.1 → XP_054214757.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917

    2. XM_054358780.1 → XP_054214755.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917

    3. XM_054358781.1 → XP_054214756.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917

    4. XM_054358779.1 → XP_054214754.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917

    5. XM_054358777.1 → XP_054214752.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917

    6. XM_054358778.1 → XP_054214753.1  fidgetin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3DVM6, Q6PIW4, Q86V18, Q8ND59, Q9H8P1, Q9H917
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PIW4.2 GenPept UniProtKB/Swiss-Prot:Q6PIW4

    Gene LinkOut

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