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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_052968.1Â RefSeqGene
- Range
-
10884..30349
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001320210.2 → NP_001307139.1  ubiquitin-like modifier-activating enzyme 5 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate 5' terminal exon, resulting in a distinct 5' UTR and the use of a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Variants 2 and 3 encode the same isoform.
- Source sequence(s)
-
AC020632, AC055732, AI681654, AK026904, BC048015, BI562266, BX537742
- Consensus CDS
-
CCDS3077.1
- UniProtKB/TrEMBL
-
E7EQ61
- Related
- ENSP00000418807.2, ENST00000494238.6
- Conserved Domains (2) summary
-
- cd00757
Location:1 → 241
- ThiF_MoeB_HesA_family; ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD ...
- pfam00899
Location:12 → 253
- ThiF; ThiF family
-
NM_001321238.2 → NP_001308167.1  ubiquitin-like modifier-activating enzyme 5 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC020632, AC055732, AI681654, AY253672, BI562266
- UniProtKB/Swiss-Prot
-
Q9GZZ9
- Conserved Domains (2) summary
-
- cd00757
Location:9 → 207
- ThiF_MoeB_HesA_family; ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD ...
- pfam00899
Location:9 → 219
- ThiF; ThiF family
-
NM_001321239.1 → NP_001308168.1  ubiquitin-like modifier-activating enzyme 5 isoform 4
Status: REVIEWED
- Source sequence(s)
-
AI681654, AK056238, AY253672, DA042045, DA477833, DA785394
- UniProtKB/Swiss-Prot
-
Q9GZZ9
- Conserved Domains (2) summary
-
- pfam00899
Location:1 → 197
- ThiF; ThiF family
- cl22428
Location:1 → 185
- E1_enzyme_family; Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common ...
-
NM_024818.6 → NP_079094.1  ubiquitin-like modifier-activating enzyme 5 isoform 1
See identical proteins and their annotated locations for NP_079094.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AC020632, AC055732, AI681654, AK056238, AY253672
- Consensus CDS
-
CCDS3076.1
- UniProtKB/Swiss-Prot
- A6NJL3, D3DNC8, Q96ST1, Q9GZZ9
- UniProtKB/TrEMBL
-
E7EQ61
- Related
- ENSP00000348565.4, ENST00000356232.10
- Conserved Domains (1) summary
-
- cd00757
Location:52 → 297
- ThiF_MoeB_HesA_family; ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD ...
-
NM_198329.4 → NP_938143.1  ubiquitin-like modifier-activating enzyme 5 isoform 2
See identical proteins and their annotated locations for NP_938143.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate 5' terminal exon, resulting in a distinct 5' UTR and the use of a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Variants 2 and 3 encode the same isoform.
- Source sequence(s)
-
AC020632, AC055732, AI681654, AY253672, BQ581736, DB457433
- Consensus CDS
-
CCDS3077.1
- UniProtKB/TrEMBL
-
E7EQ61
- Related
- ENSP00000264991.4, ENST00000264991.8
- Conserved Domains (2) summary
-
- cd00757
Location:1 → 241
- ThiF_MoeB_HesA_family; ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD ...
- pfam00899
Location:12 → 253
- ThiF; ThiF family
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12Â Reference GRCh38.p14 Primary Assembly
- Range
-
132654430..132679794
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
RNA
-
XR_007095728.1 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1Â Alternate T2T-CHM13v2.0
- Range
-
135398923..135424284
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
RNA
-
XR_008486800.1 RNA Sequence