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    CG4681 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37928, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CG4681provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0069913
    Locus tag
    Dmel_CG4681
    See related
    AllianceGenome:FB:FBgn0069913
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.29; Dmel\CG4681
    Summary
    Involved in motile cilium assembly and non-motile cilium assembly. Located in ciliary basal body. Orthologous to human TEX9 (testis expressed 9). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See CG4681 in Genome Data Viewer
    Location:
    60D5-60D7; 2-107 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24578247..24579827, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20465770..20467350, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene TFIIF-interacting CTD phosphatase Neighboring gene uncharacterized protein Neighboring gene Start1 Neighboring gene SIFamide Neighboring gene piopio Neighboring gene uncharacterized protein Neighboring gene ATP synthase, subunit F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Scrutinizing the human TEX genes in the context of human male infertility. Sieper MH, et al. Andrology, 2024 Mar. PMID 37594251
    2. A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans. Dobbelaere J, et al. EMBO J, 2023 Aug 15. PMID 37317646, Free PMC Article
    3. A genome-wide resource for the analysis of protein localisation in Drosophila. Sarov M, et al. Elife, 2016 Feb 20. PMID 26896675, Free PMC Article
    4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in motile cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in non-motile cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in ciliary basal body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4681-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24578247..24579827 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138093.4 → NP_611937.2  uncharacterized protein Dmel_CG4681 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611937.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T906, Q9W144
      Related
      FBpp0072248
      Conserved Domains (1) summary
      TIGR02168
      Location:146 → 347
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T906 Q8T906
    Q9W144 Q9W144

    Gene LinkOut

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