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    sxa2 serine carboxypeptidase Sxa2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541701, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sxa2
    Official Full Name
    serine carboxypeptidase Sxa2
    Primary source
    PomBase:SPAC1296.03c
    Locus tag
    SPOM_SPAC1296.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sxa2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (712217..714449, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cytochrome c oxidase subunit IV Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene spore wall assembly protein Neighboring gene ncRNA Neighboring gene cyclin L family cyclin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sxa2 is a serine carboxypeptidase that degrades extracellular P-factor in the fission yeast Schizosaccharomyces pombe. Ladds G, et al. Mol Microbiol, 2000 Apr. PMID 10792724
    2. The role of Sxa1 in pheromone recovery in Schizosaccharomyces pombe. Hughes M, et al. Biochem Soc Trans, 1997 May. PMID 9191273
    3. Sxa2, a carboxypeptidase that degrades extracellular pheromone in fission yeast. Ladds G, et al. Biochem Soc Trans, 1997 May. PMID 9191272
    4. Purification of Sxa2, a carboxypeptidase involved in pheromone recovery in fission yeast. Ladds G, et al. Biochem Soc Trans, 1996 Aug. PMID 8879048
    5. The sxa2-dependent inactivation of the P-factor mating pheromone in the fission yeast Schizosaccharomyces pombe. Ladds G, et al. Mol Microbiol, 1996 Apr. PMID 8861202

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables carboxypeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables serine-type carboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type carboxypeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables serine-type carboxypeptidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of MAPK cascade IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of induction of conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proteolysis involved in protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in extracellular region IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    serine carboxypeptidase Sxa2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      712217..714449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018442.3 → NP_593043.1  serine carboxypeptidase Sxa2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593043.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P32825
      Conserved Domains (2) summary
      COG2939
      Location:1 → 507
      Kex1; Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]
      cl08270
      Location:65 → 503
      Peptidase_S10; Serine carboxypeptidase
    Nucleotide Protein
    Heading Accession and Version

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