TRBV16 T cell receptor beta variable 16 [Homo sapiens (human)] - Gene

Summary

Official Symbol: TRBV16provided by HGNC
Official Full Name: T cell receptor beta variable 16provided by HGNC
Primary source: HGNC:HGNC:12191
See related: Ensembl:ENSG00000275243 IMGT/GENE-DB:TRBV16; AllianceGenome:HGNC:12191
Gene type: pseudo
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: TCRB; TCRBV16S1; TCRBV25S1; BV25S1J1.2; TCRBV25S1A2PT
Summary: Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: 7q34

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	7	NC_000007.14 (142598016..142598469)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	7	NC_060931.1 (143954912..143955365)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	7 (PATCHES)	NW_003571040.1 (781803..782256)

Chromosome 7 - NC_000007.14 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Observational study of genotype prevalence. (HuGE Navigator)
Title: T-cell receptor BV gene segment polymorphisms in healthy elderly individuals from the south of Brazil.
Observational study of gene-disease association. (HuGE Navigator)
Title: Genomic absence of the gene encoding T cell receptor Vbeta7.2 is linked to the presence of autoantibodies in Sjögren's syndrome.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Other Names

T-cell receptor TRB locus TRBV16*01
T-cell receptor beta chain V region

Gene Ontology Provided by GOA

Process	Evidence Code	Pubs
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info
involved_in cell surface receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of T cell receptor complex	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.