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    ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [ Homo sapiens (human) ]

    Gene ID: 64411, updated on 14-Nov-2024

    Summary

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    Official Symbol
    ARAP3provided by HGNC
    Official Full Name
    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3provided by HGNC
    Primary source
    HGNC:HGNC:24097
    See related
    Ensembl:ENSG00000120318 MIM:606647; AllianceGenome:HGNC:24097
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DRAG1; CENTD3
    Summary
    This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015]
    Expression
    Broad expression in lung (RPKM 9.2), fat (RPKM 7.9) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See ARAP3 in Genome Data Viewer
    Location:
    5q31.3
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (141653402..141682230, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (142179417..142208259, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (141032969..141061797, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23309 Neighboring gene histone deacetylase 3 Neighboring gene Sharpr-MPRA regulatory region 64 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16457 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16458 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23310 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23311 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141029007-141029585 Neighboring gene RELT like 2 Neighboring gene FCH and double SH3 domains 1 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr5:141037429-141038628 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16459 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141053759-141054426 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141054427-141055095 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16460 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141071853-141072386 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141072387-141072920 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141080718-141081218 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23312 Neighboring gene uncharacterized LOC124901092 Neighboring gene uncharacterized LOC124901093 Neighboring gene Sharpr-MPRA regulatory region 9303 Neighboring gene Sharpr-MPRA regulatory region 9103 Neighboring gene uncharacterized LOC124901094 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141137138-141137707 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141137708-141138276 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141138277-141138846 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141141594-141142094

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. GTPase signaling: bridging the GAP between ARF and Rho. Santy LC, et al. Curr Biol, 2002 May 14. PMID 12015138
    2. Functional reconstitution of COPI coat assembly and disassembly using chemically defined components. Reinhard C, et al. Proc Natl Acad Sci U S A, 2003 Jul 8. PMID 12832619, Free PMC Article
    3. Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3. Zhang Y, et al. Int J Mol Sci, 2023 Jan 6. PMID 36674645, Free PMC Article
    4. EST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxin. Lu Q, et al. Proc Natl Acad Sci U S A, 2004 Dec 7. PMID 15569923, Free PMC Article
    5. ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences. Craig HE, et al. Cell Signal, 2010 Feb. PMID 19786092

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ARAP3 protects from excessive formylated peptide-induced microvascular leakage by acting on endothelial cells and neutrophils.
      Title: ARAP3 protects from excessive formylated peptide-induced microvascular leakage by acting on endothelial cells and neutrophils.
    2. Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
      Title: Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
    3. Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3.
      Title: Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3.
    4. structural and binding affinity between odin and arap3
      Title: Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights.
    5. Phosphoinositide 3-OH kinase (PI3K) is input into the regulation of beta2 integrin activity, and processes dependent on its responses, by signaling through its effector ARAP3.
      Title: Phosphoinositide 3-OH kinase regulates integrin-dependent processes in neutrophils by signaling through its effector ARAP3.
    6. The structural basis for the interaction between Arap3 and Vav2, hydrophobic pockets and binding specificity.
      Title: Identification and structural basis for a novel interaction between Vav2 and Arap3.
    7. ARAP3 is a unique Src substrate that suppresses peritoneal dissemination of scirrhous gastric carcinoma cells.
      Title: ARAP3 inhibits peritoneal dissemination of scirrhous gastric carcinoma cells by regulating cell adhesion and invasion.
    8. None of the individual PH domains can bind to PtdIns(3,4,5)P3; rather, a fragment comprising two PH domains and an N-terminal linker is minimally required for binding.
      Title: ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences.
    9. ARAP3 deficiency produced by antisense expression of an ARAP3 EST impaired entry of anthrax PA and its bound toxigenic moieties into both human and mouse cells, resulting in reduced toxin sensitivity
      Title: EST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxin.
    10. The catalytic domain of ARF-GAP alone is sufficient to initiate uncoating of liposome-derived COPI-coated vesicles. ARF-GAP activity is not required for COPI coat assembly & does not seem to be an essential coat component of COPI vesicles.
      Title: Functional reconstitution of COPI coat assembly and disassembly using chemically defined components.
    Submit: New GeneRIF Correction See all GeneRIFs (12)

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ21065

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    NOT enables GTPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-3,4,5-trisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4-bisphosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoskeleton organization TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ruffle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
    Names
    ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3
    Arf and Rho GAP adapter protein 3
    PtdIns(3,4,5)P3-binding protein
    centaurin-delta-3
    phosphoinositide binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_046966.1 RefSeqGene

      Range
      5004..33832
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_022481.6 → NP_071926.4  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

      See identical proteins and their annotated locations for NP_071926.4

      Status: REVIEWED

      Source sequence(s)
      AJ310567, AK024718, BC025757, BX489939
      Consensus CDS
      CCDS4266.1
      UniProtKB/Swiss-Prot
      B4DIT1, D3DQE3, Q8WWN8
      UniProtKB/TrEMBL
      A8K1Y7
      Related
      ENSP00000239440.4, ENST00000239440.9
      Conserved Domains (11) summary
      cd09490
      Location:4 → 66
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      smart00454
      Location:12 → 64
      SAM; Sterile alpha motif
      cd04385
      Location:909 → 1084
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:289 → 381
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:398 → 479
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:676 → 786
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1212 → 1331
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      pfam00169
      Location:288 → 379
      PH; PH domain
      pfam00788
      Location:1117 → 1209
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:490 → 606
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:846 → 894
      PH-like; Pleckstrin homology-like domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      141653402..141682230 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047417514.1 → XP_047273470.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X12

    2. XM_047417513.1 → XP_047273469.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X11

      Related
      ENSP00000421826.1, ENST00000508305.5

    3. XM_047417512.1 → XP_047273468.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X10

    4. XM_047417511.1 → XP_047273467.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X9

    5. XM_047417510.1 → XP_047273466.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X8

    6. XM_005268499.2 → XP_005268556.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X6

      UniProtKB/TrEMBL
      A8K1Y7
      Conserved Domains (8) summary
      cd04385
      Location:831 → 1006
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:211 → 303
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:320 → 401
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:598 → 708
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      pfam00169
      Location:210 → 301
      PH; PH domain
      pfam00788
      Location:1039 → 1131
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:412 → 528
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:1134 → 1253
      PH-like; Pleckstrin homology-like domain

    7. XM_047417509.1 → XP_047273465.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X7

    8. XM_047417508.1 → XP_047273464.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5

    9. XM_047417507.1 → XP_047273463.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X4

    10. XM_005268498.3 → XP_005268555.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X3

      UniProtKB/TrEMBL
      A8K1Y7
      Conserved Domains (11) summary
      cd09490
      Location:4 → 66
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      smart00454
      Location:12 → 64
      SAM; Sterile alpha motif
      cd04385
      Location:909 → 1064
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:289 → 381
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:398 → 479
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:676 → 786
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1192 → 1311
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      pfam00169
      Location:288 → 379
      PH; PH domain
      pfam00788
      Location:1097 → 1189
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:490 → 606
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:846 → 894
      PH-like; Pleckstrin homology-like domain

    11. XM_047417506.1 → XP_047273462.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X2

    12. XM_047417505.1 → XP_047273461.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1

      UniProtKB/Swiss-Prot
      B4DIT1, D3DQE3, Q8WWN8

    13. XM_011537677.3 → XP_011535979.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X13

      UniProtKB/TrEMBL
      A8K1Y7
      Related
      ENSP00000421468.1, ENST00000513878.5
      Conserved Domains (8) summary
      cd04385
      Location:714 → 889
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:94 → 186
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:203 → 284
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:481 → 591
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      pfam00169
      Location:93 → 184
      PH; PH domain
      pfam00788
      Location:922 → 1014
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:295 → 411
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:1017 → 1136
      PH-like; Pleckstrin homology-like domain

    14. XM_005268500.5 → XP_005268557.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X14

      Conserved Domains (9) summary
      cd09490
      Location:4 → 66
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      smart00454
      Location:12 → 64
      SAM; Sterile alpha motif
      cd13253
      Location:289 → 381
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:398 → 479
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:676 → 786
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      pfam00169
      Location:288 → 379
      PH; PH domain
      pfam01412
      Location:490 → 606
      ArfGap; Putative GTPase activating protein for Arf
      cl02570
      Location:909 → 934
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
      cl17171
      Location:846 → 894
      PH-like; Pleckstrin homology-like domain

    15. XM_047417515.1 → XP_047273471.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X15

    RNA

    1. XR_007058626.1 RNA Sequence

    2. XR_007058625.1 RNA Sequence

    3. XR_007058624.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      142179417..142208259 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054353120.1 → XP_054209095.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X12

    2. XM_054353119.1 → XP_054209094.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X11

    3. XM_054353118.1 → XP_054209093.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X10

    4. XM_054353117.1 → XP_054209092.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X9

    5. XM_054353116.1 → XP_054209091.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X8

    6. XM_054353114.1 → XP_054209089.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X6

    7. XM_054353112.1 → XP_054209087.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X4

    8. XM_054353115.1 → XP_054209090.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X7

    9. XM_054353110.1 → XP_054209085.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X2

    10. XM_054353111.1 → XP_054209086.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X3

    11. XM_054353113.1 → XP_054209088.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5

    12. XM_054353121.1 → XP_054209096.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X13

    13. XM_054353122.1 → XP_054209097.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X14

    14. XM_054353123.1 → XP_054209098.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X15

    RNA

    1. XR_008487146.1 RNA Sequence

    2. XR_008487145.1 RNA Sequence

    3. XR_008487144.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WWN8.1 GenPept UniProtKB/Swiss-Prot:Q8WWN8

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