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    Grcc10 gene rich cluster, C10 gene [ Mus musculus (house mouse) ]

    Gene ID: 14790, updated on 2-Nov-2024

    Summary

    Official Symbol
    Grcc10provided by MGI
    Official Full Name
    gene rich cluster, C10 geneprovided by MGI
    Primary source
    MGI:MGI:1315201
    See related
    Ensembl:ENSMUSG00000072772 AllianceGenome:MGI:1315201
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C10; 2310033H05Rik
    Summary
    Predicted to be involved in several processes, including brain development; camera-type eye morphogenesis; and psychomotor behavior. Predicted to be located in cytoplasm and nuclear speck. Is expressed in several structures, including alimentary system; brain; forelimb bud; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in Temtamy syndrome. Orthologous to human C12orf57 (chromosome 12 open reading frame 57). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in kidney adult (RPKM 205.5), CNS E18 (RPKM 202.8) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Grcc10 in Genome Data Viewer
    Location:
    6 F2; 6 59.17 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (124716146..124718032, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (124739183..124741069, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4862 Neighboring gene microRNA 200c Neighboring gene protein tyrosine phosphatase, non-receptor type 6 Neighboring gene STARR-positive B cell enhancer ABC_E6486 Neighboring gene U7 small nuclear RNA Neighboring gene STARR-positive B cell enhancer ABC_E8991 Neighboring gene atrophin 1 Neighboring gene STARR-seq mESC enhancer starr_17303

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Potential readthrough

    Included gene: Atn1

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in camera-type eye morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in camera-type eye morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cognition IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cognition ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in corpus callosum morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in corpus callosum morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in post-embryonic development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in post-embryonic development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in post-embryonic development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in psychomotor behavior IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in psychomotor behavior ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of skeletal muscle contraction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of skeletal muscle contraction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in third ventricle development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in third ventricle development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein C10
    Names
    B-cell receptor-associated protein 37

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013535.2NP_038563.1  protein C10

      See identical proteins and their annotated locations for NP_038563.1

      Status: VALIDATED

      Source sequence(s)
      AI836086, AK009591, W84158
      Consensus CDS
      CCDS20525.1
      UniProtKB/Swiss-Prot
      O35127, Q545G8
      Related
      ENSMUSP00000004389.6, ENSMUST00000004389.6
      Conserved Domains (1) summary
      pfam14974
      Location:11113
      P_C10; Protein C10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      124716146..124718032 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)