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    TUG1 taurine up-regulated 1 [ Homo sapiens (human) ]

    Gene ID: 55000, updated on 2-Nov-2024

    Summary

    Official Symbol
    TUG1provided by HGNC
    Official Full Name
    taurine up-regulated 1provided by HGNC
    Primary source
    HGNC:HGNC:26066
    See related
    Ensembl:ENSG00000253352 MIM:614971; AllianceGenome:HGNC:26066
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TI-227H; LINC00080; NCRNA00080
    Summary
    Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within several processes, including mitochondrion organization; photoreceptor cell development; and spermatogenesis. Predicted to be located in mitochondrial membrane and nuclear membrane. Predicted to be active in nucleus. Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis (RPKM 36.1), endometrium (RPKM 31.7) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See TUG1 in Genome Data Viewer
    Location:
    22q12.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (30969265..30979395)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (31432823..31442955)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (31365251..31375381)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein 2 Neighboring gene uncharacterized LOC107985544 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18846 Neighboring gene eukaryotic translation initiation factor 4H pseudogene 2 Neighboring gene MORC2 antisense RNA 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:31335586-31335801 Neighboring gene MORC family CW-type zinc finger 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18847 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13620 Neighboring gene MPRA-validated peak4481 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:31439932-31440502 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:31440503-31441072 Neighboring gene RNA, 7SL, cytoplasmic 633, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13621 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13622 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13623 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:31481712-31482338 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:31492256-31492830 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:31492831-31493404 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:31499788-31500738 Neighboring gene smoothelin

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Clone Names

    • FLJ20618, MGC46067

    General protein information

    Preferred Names
    taurine up-regulated 1
    Names
    taurine upregulated gene 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396518.1NP_001383447.1  taurine up-regulated 1

      Status: VALIDATED

      Source sequence(s)
      AC004542
      Consensus CDS
      CCDS93148.1
      UniProtKB/Swiss-Prot
      A0A6I8PU40
      Related
      ENSP00000501406.2, ENST00000644773.3
    2. NM_001398476.1NP_001385405.1  taurine up-regulated 1

      Status: VALIDATED

      Source sequence(s)
      AC004542
      Consensus CDS
      CCDS93148.1
      UniProtKB/Swiss-Prot
      A0A6I8PU40
    3. NM_001398477.1NP_001385406.1  taurine up-regulated 1

      Status: VALIDATED

      Source sequence(s)
      AC004542
      Consensus CDS
      CCDS93148.1
      UniProtKB/Swiss-Prot
      A0A6I8PU40
    4. NM_001398478.1NP_001385407.1  taurine up-regulated 1

      Status: VALIDATED

      Source sequence(s)
      AC004542
      Consensus CDS
      CCDS93148.1
      UniProtKB/Swiss-Prot
      A0A6I8PU40
    5. NM_001398479.1NP_001385408.1  taurine up-regulated 1

      Status: VALIDATED

      Source sequence(s)
      AC004542
      Consensus CDS
      CCDS93148.1
      UniProtKB/Swiss-Prot
      A0A6I8PU40
      Related
      ENST00000643071.1
    6. NM_001398480.1NP_001385409.1  taurine up-regulated 1

      Status: VALIDATED

      Source sequence(s)
      AC004542
      Consensus CDS
      CCDS93148.1
      UniProtKB/Swiss-Prot
      A0A6I8PU40

    RNA

    1. NR_152867.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004542
      Related
      ENST00000646496.1
    2. NR_152868.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004542

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      30969265..30979395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      31432823..31442955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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