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    Rpp25 ribonuclease P and MRP subunit p25 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315705, updated on 2-Nov-2024

    Summary

    Official Symbol
    Rpp25provided by RGD
    Official Full Name
    ribonuclease P and MRP subunit p25provided by RGD
    Primary source
    RGD:1305290
    See related
    EnsemblRapid:ENSRNOG00000018812 AllianceGenome:RGD:1305290
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in centriolar satellite and nucleoplasm. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Orthologous to human RPP25 (ribonuclease P and MRP subunit p25). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See Rpp25 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (66803262..66804642)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (57907352..57908732)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (62283336..62284716)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene phosphopantothenoylcysteine decarboxylase Neighboring gene secretory carrier membrane protein 5 Neighboring gene uncharacterized LOC134480187 Neighboring gene small nucleolar RNA, H/ACA box 3C

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribonuclease P RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribonuclease P RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    contributes_to ribonuclease P activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ribonuclease P activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA 5'-leader removal IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in tRNA 5'-leader removal ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA 5'-leader removal ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in centriolar satellite IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    part_of multimeric ribonuclease P complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of multimeric ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonuclease MRP complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ribonuclease P protein subunit p25
    Names
    RNase P protein subunit p25
    ribonuclease P 25 subunit
    ribonuclease P/MRP 25 subunit
    NP_001012124.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012124.1NP_001012124.1  ribonuclease P protein subunit p25

      See identical proteins and their annotated locations for NP_001012124.1

      Status: PROVISIONAL

      Source sequence(s)
      BC087592
      UniProtKB/Swiss-Prot
      Q5PPN2
      UniProtKB/TrEMBL
      A6J4V4
      Related
      ENSRNOP00000025408.2, ENSRNOT00000025410.5
      Conserved Domains (1) summary
      pfam01918
      Location:37101
      Alba; Alba

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      66803262..66804642
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)