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    Spatc1 spermatogenesis and centriole associated 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315091, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Spatc1provided by RGD
    Official Full Name
    spermatogenesis and centriole associated 1provided by RGD
    Primary source
    RGD:1565316
    See related
    EnsemblRapid:ENSRNOG00000029590 AllianceGenome:RGD:1565316
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565316
    Summary
    Predicted to enable gamma-tubulin binding activity. Predicted to be located in cytoplasm. Predicted to be active in centrosome. Orthologous to human SPATC1 (spermatogenesis and centriole associated 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 132.6) and Kidney (RPKM 75.5) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Spatc1 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (109863794..109888145)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (107980857..108007716)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117326279..117349957)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene plectin Neighboring gene poly (ADP-ribose) polymerase family, member 10 Neighboring gene uncharacterized LOC120093816 Neighboring gene glutamate ionotropic receptor NMDA type subunit associated protein 1 Neighboring gene transfer RNA leucine (anticodon AAG) 12 Neighboring gene sphingomyelin phosphodiesterase 5 Neighboring gene 5-oxoprolinase (ATP-hydrolysing) Neighboring gene exosome component 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Speriolin is a novel human and mouse sperm centrosome protein. Goto M, et al. Hum Reprod, 2010 Aug. PMID 20542897, Free PMC Article
    2. Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20. Goto M, et al. J Biol Chem, 2004 Oct 1. PMID 15280373
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables gamma-tubulin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    speriolin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001115026.1 → NP_001108498.1  speriolin

      See identical proteins and their annotated locations for NP_001108498.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473950
      UniProtKB/TrEMBL
      A6HS75, B0BMZ4, F7EX86
      Related
      ENSRNOP00000041285.3, ENSRNOT00000050522.5
      Conserved Domains (2) summary
      pfam15058
      Location:1 → 256
      Speriolin_N; Speriolin N terminus
      pfam15059
      Location:326 → 472
      Speriolin_C; Speriolin C-terminus

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      109863794..109888145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079242.2 → XP_038935170.1  speriolin isoform X2

      Conserved Domains (2) summary
      pfam15058
      Location:1 → 41
      Speriolin_N; Speriolin N-terminus
      pfam15059
      Location:181 → 327
      Speriolin_C; Speriolin C-terminus

    2. XM_039079239.2 → XP_038935167.1  speriolin isoform X1

      Conserved Domains (2) summary
      pfam15058
      Location:2 → 175
      Speriolin_N; Speriolin N-terminus
      pfam15059
      Location:245 → 391
      Speriolin_C; Speriolin C-terminus

    3. XM_039079240.2 → XP_038935168.1  speriolin isoform X1

      Conserved Domains (2) summary
      pfam15058
      Location:2 → 175
      Speriolin_N; Speriolin N-terminus
      pfam15059
      Location:245 → 391
      Speriolin_C; Speriolin C-terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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