Omg oligodendrocyte-myelin glycoprotein [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Omgprovided by RGD
Full Name: oligodendrocyte-myelin glycoproteinprovided by RGD
Primary source: RGD:1359125
See related: EnsemblRapid:ENSRNOG00000082212 AllianceGenome:RGD:1359125
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in neuron projection regeneration. Predicted to act upstream of or within regulation of collateral sprouting of intact axon in response to injury. Orthologous to human OMG (oligodendrocyte myelin glycoprotein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 437.5), Lung (RPKM 38.6) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q25

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (64959316..64962050, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (64461350..64464084, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (66845654..66848388, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

the change of neuronal OMgp expression might be involved in reconnection of neural circuit between axotomized facial neuron and upper motor neuron after transection
Title: Reduction of oligodendrocyte myelin glycoprotein expression following facial nerve transection.

Submit: New GeneRIF Correction

General gene information

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Markers

Omg (e-PCR), detects polymorphism
- UniSTS:495849

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in neuron projection regeneration	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within neuron projection regeneration	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of collateral sprouting of intact axon in response to injury	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: oligodendrocyte-myelin glycoprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005898.3 → NP_001005898.3 oligodendrocyte-myelin glycoprotein precursor

See identical proteins and their annotated locations for NP_001005898.3

Status: VALIDATED

Source sequence(s)

BC087723, BF390746, CF978186

UniProtKB/TrEMBL

A6HH87, F7EYB9, Q7TQ25

Related

ENSRNOP00000018892.5, ENSRNOT00000018891.6

Conserved Domains (4) summary

smart00013
Location:28 → 62

LRRNT; Leucine rich repeat N-terminal domain

cd00116
Location:77 → 233

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00033
Location:40 → 59

LRR_RI; leucine-rich repeat [structural motif]

pfam13855
Location:170 → 229

LRR_8; Leucine rich repeat