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    Tpgs2 tubulin polyglutamylase complex subunit 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361301, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tpgs2provided by RGD
    Official Full Name
    tubulin polyglutamylase complex subunit 2provided by RGD
    Primary source
    RGD:1310571
    See related
    EnsemblRapid:ENSRNOG00000054118 AllianceGenome:RGD:1310571
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pgs2; RGD1310571
    Summary
    Predicted to be involved in protein polyglutamylation. Predicted to be located in centriolar satellite; cytoplasm; and microtubule. Orthologous to human TPGS2 (tubulin polyglutamylase complex subunit 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 122.6), Brain (RPKM 106.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tpgs2 in Genome Data Viewer
    Location:
    18p12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (16707336..16764278, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (16432628..16489604, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (17339033..17396886, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene formin homology 2 domain containing 3 Neighboring gene uncharacterized LOC134482922 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene KIAA1328 homolog Neighboring gene CUGBP, Elav-like family member 4 Neighboring gene uncharacterized LOC120098197

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein polyglutamylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in centriolar satellite IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tubulin polyglutamylase complex subunit 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014147.1 → NP_001014169.2  tubulin polyglutamylase complex subunit 2

      See identical proteins and their annotated locations for NP_001014169.2

      Status: VALIDATED

      Source sequence(s)
      BC079332
      UniProtKB/Swiss-Prot
      Q6AXS8
      UniProtKB/TrEMBL
      A6J2L4
      Related
      ENSRNOP00000084578.1, ENSRNOT00000093690.3
      Conserved Domains (1) summary
      smart00860
      Location:43 → 192
      SMI1_KNR4; SMI1 / KNR4 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      16707336..16764278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039096955.2 → XP_038952883.1  tubulin polyglutamylase complex subunit 2 isoform X1

      Conserved Domains (1) summary
      smart00860
      Location:2 → 133
      SMI1_KNR4; SMI1 / KNR4 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AXS8.2 GenPept UniProtKB/Swiss-Prot:Q6AXS8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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