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    Lrrc24 leucine rich repeat containing 24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362945, updated on 10-Jul-2024

    Summary

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    Official Symbol
    Lrrc24provided by RGD
    Official Full Name
    leucine rich repeat containing 24provided by RGD
    Primary source
    RGD:1308720
    See related
    EnsemblRapid:ENSRNOG00000016204 AllianceGenome:RGD:1308720
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308720
    Summary
    Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. Orthologous to human LRRC24 (leucine rich repeat containing 24). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 46.0), Kidney (RPKM 18.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrrc24 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (110317935..110325201, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (108437296..108444561, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117779733..117786872, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 3 Neighboring gene RecQ like helicase 4 Neighboring gene leucine rich repeat containing 14 Neighboring gene similar to human chromosome 8 open reading frame 82 Neighboring gene Rho GTPase activating protein 39 Neighboring gene uncharacterized LOC134479930

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Um JW, et al. Cell Rep, 2014 Mar 27. PMID 24613359, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of synapse assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135896.1 → NP_001129368.1  leucine-rich repeat-containing protein 24 precursor

      See identical proteins and their annotated locations for NP_001129368.1

      Status: PROVISIONAL

      Source sequence(s)
      BC127521
      UniProtKB/TrEMBL
      A0JPN8
      Conserved Domains (6) summary
      TIGR00864
      Location:188 → 259
      PCC; polycystin cation channel protein
      sd00033
      Location:61 → 83
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:84 → 142
      LRR_8; Leucine rich repeat
      pfam13927
      Location:267 → 357
      Ig_3; Immunoglobulin domain
      cd00096
      Location:267 → 271
      Ig; Ig strand A [structural motif]
      cd21340
      Location:63 → 212
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      110317935..110325201 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008765581.4 → XP_008763803.1  leucine-rich repeat-containing protein 24 isoform X1

      See identical proteins and their annotated locations for XP_008763803.1

      UniProtKB/TrEMBL
      A0JPN8
      Conserved Domains (6) summary
      TIGR00864
      Location:188 → 259
      PCC; polycystin cation channel protein
      sd00033
      Location:61 → 83
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:84 → 142
      LRR_8; Leucine rich repeat
      pfam13927
      Location:267 → 357
      Ig_3; Immunoglobulin domain
      cd00096
      Location:267 → 271
      Ig; Ig strand A [structural motif]
      cd21340
      Location:63 → 212
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    2. XM_039079560.2 → XP_038935488.1  leucine-rich repeat-containing protein 24 isoform X1

      UniProtKB/TrEMBL
      A0JPN8
      Related
      ENSRNOP00000029554.5, ENSRNOT00000030517.7
      Conserved Domains (6) summary
      TIGR00864
      Location:188 → 259
      PCC; polycystin cation channel protein
      sd00033
      Location:61 → 83
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:84 → 142
      LRR_8; Leucine rich repeat
      pfam13927
      Location:267 → 357
      Ig_3; Immunoglobulin domain
      cd00096
      Location:267 → 271
      Ig; Ig strand A [structural motif]
      cd21340
      Location:63 → 212
      PPP1R42; protein phosphatase 1 regulatory subunit 42
    Nucleotide Protein Strain
    Heading Accession and Version

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