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    LOC728743 zinc finger domain-containing protein LOC728743 [ Homo sapiens (human) ]

    Gene ID: 728743, updated on 17-Sep-2024

    Summary

    Gene symbol
    LOC728743
    Gene description
    zinc finger domain-containing protein LOC728743
    See related
    Ensembl:ENSG00000284691
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in lymph node (RPKM 5.1), spleen (RPKM 4.4) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See LOC728743 in Genome Data Viewer
    Location:
    7q36.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (150400702..150412470)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (151579025..151590794)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (150097790..150109558)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene REPIN1 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26823 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150065484-150066288 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150066289-150067094 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150067095-150067899 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26824 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26825 Neighboring gene replication initiator 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26826 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18778 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26827 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150078931-150079888 Neighboring gene ZNF775 antisense RNA 1 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150080845-150081800 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150083270-150083842 Neighboring gene zinc finger protein 775 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150083843-150084413 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150085648-150086246 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150096281-150096868 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150096869-150097456 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150097787-150098311 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150098312-150098835 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:150098842-150099517 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150099518-150100192 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:150100193-150100867 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18779 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:150103235-150103743 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26828 Neighboring gene uncharacterized LOC124901773 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18780 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26829 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26830 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26831 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26832 Neighboring gene long intergenic non-protein coding RNA 996

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    zinc finger protein LOC728743

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395974.1NP_001382903.1  zinc finger protein LOC728743 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC073111
      Consensus CDS
      CCDS94231.1
      UniProtKB/TrEMBL
      B7ZLF3
      Related
      ENSP00000492887.1, ENST00000498682.3
      Conserved Domains (2) summary
      COG5048
      Location:36188
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:7090
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001395975.1NP_001382904.1  zinc finger protein LOC728743 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC073111
      Consensus CDS
      CCDS94231.1
      UniProtKB/TrEMBL
      B7ZLF3
      Conserved Domains (2) summary
      COG5048
      Location:36188
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:7090
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_001395976.1NP_001382905.1  zinc finger protein LOC728743 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC073111
      Consensus CDS
      CCDS94231.1
      UniProtKB/TrEMBL
      B7ZLF3
      Related
      ENSP00000493097.1, ENST00000642087.2
      Conserved Domains (2) summary
      COG5048
      Location:36188
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:7090
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. NM_001395977.1NP_001382906.1  zinc finger protein LOC728743 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC073111
      Consensus CDS
      CCDS94230.1
      UniProtKB/TrEMBL
      A0A286YF50
      Related
      ENSP00000493012.1, ENST00000641717.1
      Conserved Domains (2) summary
      PHA00733
      Location:3677
      PHA00733; hypothetical protein
      sd00017
      Location:3956
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RNA

    1. NR_173085.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC073111
      Related
      ENST00000641330.1
    2. NR_173086.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC073111
    3. NR_173087.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC073111
    4. NR_173088.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC073111

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      150400702..150412470
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047420792.1XP_047276748.1  zinc finger protein LOC728743 isoform X3

      UniProtKB/TrEMBL
      A0A286YF50
    2. XM_047420787.1XP_047276743.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    3. XM_047420786.1XP_047276742.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    4. XM_047420785.1XP_047276741.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    5. XM_047420788.1XP_047276744.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    6. XM_047420791.1XP_047276747.1  zinc finger protein LOC728743 isoform X3

      UniProtKB/TrEMBL
      A0A286YF50
    7. XM_047420789.1XP_047276745.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    8. XM_047420790.1XP_047276746.1  zinc finger protein LOC728743 isoform X2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      151579025..151590794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054358925.1XP_054214900.1  zinc finger protein LOC728743 isoform X3

      UniProtKB/TrEMBL
      A0A286YF50
    2. XM_054358920.1XP_054214895.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    3. XM_054358919.1XP_054214894.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    4. XM_054358918.1XP_054214893.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    5. XM_054358921.1XP_054214896.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    6. XM_054358924.1XP_054214899.1  zinc finger protein LOC728743 isoform X3

      UniProtKB/TrEMBL
      A0A286YF50
    7. XM_054358917.1XP_054214892.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    8. XM_054358922.1XP_054214897.1  zinc finger protein LOC728743 isoform X1

      UniProtKB/TrEMBL
      B7ZLF3
    9. XM_054358923.1XP_054214898.1  zinc finger protein LOC728743 isoform X2

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001080852.1: Suppressed sequence

      Description
      NM_001080852.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    2. NR_027237.1: Suppressed sequence

      Description
      NR_027237.1: This RefSeq was removed because it is now thought that this gene does encode a protein.