U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PAGE5 PAGE family member 5 [ Homo sapiens (human) ]

    Gene ID: 90737, updated on 17-Sep-2024

    Summary

    Official Symbol
    PAGE5provided by HGNC
    Official Full Name
    PAGE family member 5provided by HGNC
    Primary source
    HGNC:HGNC:29992
    See related
    Ensembl:ENSG00000158639 MIM:301009; AllianceGenome:HGNC:29992
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CT16; CT16.1; CT16.2; GAGEE1; PAGE-5
    Summary
    This gene is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. The encoded protein may protect cells from programmed cell death. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jan 2015]
    Expression
    Restricted expression toward testis (RPKM 6.1) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PAGE5 in Genome Data Viewer
    Location:
    Xp11.21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (55220346..55224108)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (54513490..54517252)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (55246779..55250541)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene X antigen family member 3-like Neighboring gene MT-RNR2 like 10 (pseudogene) Neighboring gene small nucleolar RNA, H/ACA box 109 Neighboring gene PAGE family member 3 Neighboring gene PAGE family member 5 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    P antigen family member 5
    Names
    P antigen family, member 5 (prostate associated)
    cancer/testis antigen 16.1
    cancer/testis antigen family 16, member 1
    cancer/testis antigen family 16, member 2
    g antigen family E member 1
    prostate-associated gene 5 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013435.3NP_001013453.1  P antigen family member 5 isoform 2

      See identical proteins and their annotated locations for NP_001013453.1

      Status: REVIEWED

      Source sequence(s)
      AL158819, BP429046, BQ437151
      Consensus CDS
      CCDS35306.1
      UniProtKB/TrEMBL
      Q5JUL1
      Related
      ENSP00000364093.3, ENST00000374955.8
      Conserved Domains (1) summary
      pfam05831
      Location:1109
      GAGE; GAGE protein
    2. NM_130467.5NP_569734.2  P antigen family member 5 isoform 1

      See identical proteins and their annotated locations for NP_569734.2

      Status: REVIEWED

      Source sequence(s)
      AL158819, BC009230, BP429046, BQ437151
      Consensus CDS
      CCDS14368.1
      UniProtKB/Swiss-Prot
      Q2NL97, Q5JUL0, Q8WWL9, Q96GU1
      Related
      ENSP00000289619.5, ENST00000289619.9
      Conserved Domains (1) summary
      pfam05831
      Location:21126
      GAGE; GAGE protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      55220346..55224108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      54513490..54517252
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)