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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_042147.1 RefSeqGene
- Range
-
4704..94639
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_080722.4 → NP_542453.2 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform 2 preproprotein
See identical proteins and their annotated locations for NP_542453.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) represents the shorter transcript and encodes the shorter isoform (2).
- Source sequence(s)
-
AF358666, AF366351, AK128469, AL355344, AL358817, CN398634
- Consensus CDS
-
CCDS7306.1
- UniProtKB/Swiss-Prot
- Q5T4G0, Q5T4G1, Q8TE55, Q8TEY8, Q8WXS8
- Related
- ENSP00000362303.1, ENST00000373207.2
- Conserved Domains (5) summary
-
- smart00209
Location:555 → 607
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:273 → 457
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01562
Location:104 → 206
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:714 → 829
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam06679
Location:1111 → 1185
- DUF1180; Protein of unknown function (DUF1180)
-
NM_139155.3 → NP_631894.2 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform 1 precursor
See identical proteins and their annotated locations for NP_631894.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (1) is longer than isoform 2, but may undergo proteolytic processing similar to isoform 2.
- Source sequence(s)
-
AF366351, AK128469, AL355344, AL358817, CN398634
- Consensus CDS
-
CCDS7307.1
- UniProtKB/Swiss-Prot
-
Q8WXS8
- Related
- ENSP00000362304.1, ENST00000373208.5
- Conserved Domains (5) summary
-
- smart00209
Location:558 → 610
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:273 → 460
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01562
Location:104 → 206
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:717 → 832
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam06679
Location:1114 → 1188
- DUF1180; Protein of unknown function (DUF1180)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000010.11 Reference GRCh38.p14 Primary Assembly
- Range
-
70672506..70762441
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011539300.3 → XP_011537602.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1
- Conserved Domains (6) summary
-
- smart00209
Location:558 → 610
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:273 → 460
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01562
Location:104 → 206
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:717 → 812
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam06679
Location:944 → 1018
- DUF1180; Protein of unknown function (DUF1180)
- cl15456
Location:508 → 543
- ADAM_CR; ADAM cysteine-rich
-
XM_011539308.3 → XP_011537610.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X4
See identical proteins and their annotated locations for XP_011537610.1
- Conserved Domains (5) summary
-
- smart00209
Location:558 → 610
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:273 → 460
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01562
Location:104 → 206
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:717 → 757
- ADAM_spacer1; ADAM-TS Spacer 1
- cl15456
Location:508 → 543
- ADAM_CR; ADAM cysteine-rich
-
XM_011539306.3 → XP_011537608.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X4
See identical proteins and their annotated locations for XP_011537608.1
- Conserved Domains (5) summary
-
- smart00209
Location:558 → 610
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:273 → 460
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01562
Location:104 → 206
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:717 → 757
- ADAM_spacer1; ADAM-TS Spacer 1
- cl15456
Location:508 → 543
- ADAM_CR; ADAM cysteine-rich
-
XM_011539303.3 → XP_011537605.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X3
- Conserved Domains (5) summary
-
- smart00209
Location:558 → 610
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:273 → 460
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01562
Location:104 → 206
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:717 → 812
- ADAM_spacer1; ADAM-TS Spacer 1
- cl15456
Location:508 → 543
- ADAM_CR; ADAM cysteine-rich
-
XM_011539307.3 → XP_011537609.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X4
See identical proteins and their annotated locations for XP_011537609.1
- Conserved Domains (5) summary
-
- smart00209
Location:558 → 610
- TSP1; Thrombospondin type 1 repeats
- cd04273
Location:273 → 460
- ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
- pfam01562
Location:104 → 206
- Pep_M12B_propep; Reprolysin family propeptide
- pfam05986
Location:717 → 757
- ADAM_spacer1; ADAM-TS Spacer 1
- cl15456
Location:508 → 543
- ADAM_CR; ADAM cysteine-rich
-
XM_011539302.2 → XP_011537604.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2
See identical proteins and their annotated locations for XP_011537604.1
- Conserved Domains (5) summary
-
- smart00209
Location:246 → 298
- TSP1; Thrombospondin type 1 repeats
- pfam00090
Location:666 → 712
- TSP_1; Thrombospondin type 1 domain
- pfam05986
Location:405 → 520
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam06679
Location:802 → 876
- DUF1180; Protein of unknown function (DUF1180)
- cl00064
Location:1 → 148
- ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...
-
XM_011539301.2 → XP_011537603.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2
See identical proteins and their annotated locations for XP_011537603.1
- Conserved Domains (5) summary
-
- smart00209
Location:246 → 298
- TSP1; Thrombospondin type 1 repeats
- pfam00090
Location:666 → 712
- TSP_1; Thrombospondin type 1 domain
- pfam05986
Location:405 → 520
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam06679
Location:802 → 876
- DUF1180; Protein of unknown function (DUF1180)
- cl00064
Location:1 → 148
- ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...
-
XM_011539309.2 → XP_011537611.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X5
- Conserved Domains (4) summary
-
- smart00209
Location:78 → 130
- TSP1; Thrombospondin type 1 repeats
- pfam00090
Location:498 → 544
- TSP_1; Thrombospondin type 1 domain
- pfam05986
Location:237 → 352
- ADAM_spacer1; ADAM-TS Spacer 1
- pfam06679
Location:634 → 708
- DUF1180; Protein of unknown function (DUF1180)
RNA
-
XR_001747025.2 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060934.1 Alternate T2T-CHM13v2.0
- Range
-
71542163..71632194
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054364860.1 → XP_054220835.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1
-
XM_054364866.1 → XP_054220841.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X4
-
XM_054364865.1 → XP_054220840.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X4
-
XM_054364863.1 → XP_054220838.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X3
-
XM_054364864.1 → XP_054220839.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X4
-
XM_054364862.1 → XP_054220837.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2
-
XM_054364861.1 → XP_054220836.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2
-
XM_054364867.1 → XP_054220842.1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X5
RNA
-
XR_008488168.1 RNA Sequence