U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    DSS1 exoribonuclease II [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855331, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    DSS1
    Official Full Name
    exoribonuclease II
    Primary source
    SGD:S000004900
    Locus tag
    YMR287C
    See related
    AllianceGenome:SGD:S000004900; FungiDB:YMR287C; VEuPathDB:YMR287C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MSU1
    Summary
    Enables exoribonuclease II activity. Involved in mitochondrial RNA catabolic process. Located in mitochondrion. Part of mitochondrial degradosome. [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DSS1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (842436..845345, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene RNA exonuclease Neighboring gene mitochondrial 54S ribosomal protein YmL33 Neighboring gene U2 snRNP complex subunit HSH155 Neighboring gene aminodeoxychorismate lyase ABZ2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ccm1p is a 15S rRNA primary transcript processing factor as elucidated by a novel in vivo system in Saccharomyces cerevisiae. Moreno JI, et al. Curr Genet, 2020 Aug. PMID 32152734, Free PMC Article
    2. Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation. Guo XE, et al. J Biol Chem, 2011 Nov 4. PMID 21911497, Free PMC Article
    3. Assays of the helicase, ATPase, and exoribonuclease activities of the yeast mitochondrial degradosome. Malecki M, et al. Methods Mol Biol, 2010. PMID 20225161
    4. In vitro reconstitution and characterization of the yeast mitochondrial degradosome complex unravels tight functional interdependence. Malecki M, et al. J Mol Biol, 2007 Sep 7. PMID 17658549
    5. The novel nuclear gene DSS-1 of Saccharomyces cerevisiae is necessary for mitochondrial biogenesis. Dmochowska A, et al. Curr Genet, 1995 Jul. PMID 8590460

    See all (57) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These data enabled the discovery of links between components of the mRNA export and splicing machineries and Sem1/Dss1, a component of the 19S proteasome.
      Title: A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables exoribonuclease II activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables exoribonuclease II activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial RNA catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial degradosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    exoribonuclease II
    NP_014014.1
    • 3'-5' exoribonuclease; component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      842436..845345 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182794.1 → NP_014014.1  TPA: exoribonuclease II [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014014.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0B4, P39112
      UniProtKB/TrEMBL
      G2WKZ6, N1P614
      Conserved Domains (1) summary
      COG0557
      Location:385 → 967
      VacB; Exoribonuclease R [Transcription]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P39112.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools