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    IRC18 Irc18p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853414, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IRC18
    Official Full Name
    Irc18p
    Primary source
    SGD:S000003574
    Locus tag
    YJL037W
    See related
    AllianceGenome:SGD:S000003574; FungiDB:YJL037W; VEuPathDB:YJL037W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    OSW6
    Summary
    Involved in ascospore wall assembly. Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See IRC18 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (376662..377336)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene tRNA-Arg Neighboring gene Loh1p Neighboring gene tRNA-Val Neighboring gene Snx4p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The core meiotic transcriptome in budding yeasts. Primig M, et al. Nat Genet, 2000 Dec. PMID 11101837
    2. Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. Roberts CJ, et al. Science, 2000 Feb 4. PMID 10657304
    3. The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. Boer VM, et al. J Biol Chem, 2003 Jan 31. PMID 12414795
    4. Genome-wide responses to mitochondrial dysfunction. Epstein CB, et al. Mol Biol Cell, 2001 Feb. PMID 11179416, Free PMC Article
    5. The transcriptional program of sporulation in budding yeast. Chu S, et al. Science, 1998 Oct 23. PMID 9784122

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Irc18p
    NP_012497.3
    • Protein involved in outer spore wall assembly; possible role in assembly of the dityrosine layer; similar to adjacent ORF, LOH1; irc18 loh1 double mutant exhibits reduced dityrosine fluorescence relative to single mutants; SWAT-GFP fusion protein localizes to the ER and vacuole, while mCherry fusion localizes to the vacuole; expression induced in respiratory-deficient cells and carbon-limited chemostat culture; null mutant displays increased levels of spontaneous Rad52p foci

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      376662..377336
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181471.3 → NP_012497.3  TPA: Irc18p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012497.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWE6, P47056
      UniProtKB/TrEMBL
      A6ZPT9, B3LQ74, C7GSQ9, C8ZBC2, G2WGY1, N1P8J3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47056.1

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