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    GTO3 omega-class glutathione transferase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855292, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GTO3
    Official Full Name
    omega-class glutathione transferase
    Primary source
    SGD:S000004863
    Locus tag
    YMR251W
    See related
    AllianceGenome:SGD:S000004863; FungiDB:YMR251W; VEuPathDB:YMR251W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See GTO3 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (772915..774015)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene glutamate decarboxylase GAD1 Neighboring gene Hor7p Neighboring gene Mlo1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary relationships between Saccharomyces cerevisiae and other fungal species as determined from genome comparisons. Herrero E. Rev Iberoam Micol, 2005 Dec. PMID 16499414
    2. Saccharomyces cerevisiae cells have three Omega class glutathione S-transferases acting as 1-Cys thiol transferases. Garcerá A, et al. Biochem J, 2006 Sep 1. PMID 16709151, Free PMC Article
    3. A peroxisomal glutathione transferase of Saccharomyces cerevisiae is functionally related to sulfur amino acid metabolism. Barreto L, et al. Eukaryot Cell, 2006 Oct. PMID 16936141, Free PMC Article
    4. Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase. Stundon JL, et al. G3 (Bethesda), 2015 Oct 19. PMID 26483010, Free PMC Article
    5. Functional analysis with a barcoder yeast gene overexpression system. Douglas AC, et al. G3 (Bethesda), 2012 Oct. PMID 23050238, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. act as 1-Cys thiol transferases
      Title: Saccharomyces cerevisiae cells have three Omega class glutathione S-transferases acting as 1-Cys thiol transferases.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutathione transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glutathione metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    omega-class glutathione transferase
    NP_013977.1
    • Omega class glutathione transferase; putative cytosolic localization

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      772915..774015
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182757.1 → NP_013977.1  TPA: omega-class glutathione transferase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013977.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W077, Q04806
      UniProtKB/TrEMBL
      A6ZMW6, B3LMD9, B5VQ19, C7GRA1, C8ZFB6
      Conserved Domains (1) summary
      COG0435
      Location:1 → 366
      ECM4; Glutathionyl-hydroquinone reductase [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04806.1

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