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    PF3D7_1027300 peroxiredoxin [ Plasmodium falciparum 3D7 ]

    Gene ID: 810425, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1027300
    Gene description
    peroxiredoxin
    Locus tag
    PF3D7_1027300
    See related
    PlasmoDB:PF3D7_1027300; VEuPathDB:PF3D7_1027300
    Gene type
    protein coding
    RNA name
    peroxiredoxin
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1027300 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    3
    Sequence:
    Chromosome: 10; NC_037281.1 (1140589..1142602, complement)

    Chromosome 10 - NC_037281.1Genomic Context describing neighboring genes Neighboring gene U3 small nucleolar ribonucleoprotein protein MPP10, putative Neighboring gene mitochondrial ribosomal protein S22 precursor, putative Neighboring gene DNA-directed RNA polymerase II subunit RPB7, putative Neighboring gene conserved Plasmodium protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037281.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genome-wide chromatin-associated nuclear peroxiredoxin from the malaria parasite Plasmodium falciparum. Richard D, et al. J Biol Chem, 2011 Apr 1. PMID 21282103, Free PMC Article
    2. Identification of peptides with high red blood cell and hepatocyte binding activity in the Plasmodium falciparum multi-stage invasion proteins: PfSPATR and MCP-1. Curtidor H, et al. Biochimie, 2008 Nov-Dec. PMID 18832006
    3. Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. Briquet S, et al. PLoS One, 2018. PMID 30379851, Free PMC Article
    4. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article
    5. A protein interaction network of the malaria parasite Plasmodium falciparum. LaCount DJ, et al. Nature, 2005 Nov 3. PMID 16267556

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A genome-wide chromatin-associated nuclear peroxiredoxin from the malaria parasite Plasmodium falciparum.
      Title: A genome-wide chromatin-associated nuclear peroxiredoxin from the malaria parasite Plasmodium falciparum.
    2. This work reports the fine mapping of PfSPATR and MCP-1 binding regions to HepG2 cells and human red blood cell (RBCs) as well as their role during merozoite in vitro invasion of RBCs.
      Title: Identification of peptides with high red blood cell and hepatocyte binding activity in the Plasmodium falciparum multi-stage invasion proteins: PfSPATR and MCP-1.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxiredoxin
    XP_001347552.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037281.1 Reference assembly

      Range
      1140589..1142602 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001347516.1 → XP_001347552.1  peroxiredoxin [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001347552.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024X7A6, A0A0L7M3G5, A0A2I0BR47, O76465, Q8IJD0, W4IFG2, W7FE43
      Conserved Domains (1) summary
      cd03017
      Location:18 → 153
      PRX_BCP; Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing ...
    Nucleotide Protein
    Heading Accession and Version

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