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    PF3D7_1016400 serine/threonine protein kinase, FIKK family [ Plasmodium falciparum 3D7 ]

    Gene ID: 810318, updated on 18-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1016400
    Gene description
    serine/threonine protein kinase, FIKK family
    Locus tag
    PF3D7_1016400
    See related
    PlasmoDB:PF3D7_1016400; VEuPathDB:PF3D7_1016400
    Gene type
    protein coding
    RNA name
    serine/threonine protein kinase, FIKK family
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1016400 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    3
    Sequence:
    Chromosome: 10; NC_037281.1 (656709..659027, complement)

    Chromosome 10 - NC_037281.1Genomic Context describing neighboring genes Neighboring gene Rab3 GTPase-activating protein non-catalytic subunit, putative Neighboring gene GBP130 protein Neighboring gene Plasmodium exported protein (PHISTc), unknown function Neighboring gene Plasmodium exported protein (PHISTc), unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037281.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of essential exported Plasmodium falciparum protein kinases in malaria-infected red blood cells. Siddiqui G, et al. Br J Haematol, 2020 Mar. PMID 31650539
    2. An exported kinase family mediates species-specific erythrocyte remodelling and virulence in human malaria. Davies H, et al. Nat Microbiol, 2020 Jun. PMID 32284562, Free PMC Article
    3. A protein interaction network of the malaria parasite Plasmodium falciparum. LaCount DJ, et al. Nature, 2005 Nov 3. PMID 16267556
    4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Process Evidence Code Pubs
    acts_upstream_of_or_within protein phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within symbiont-mediated perturbation of host process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Maurer's cleft IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine protein kinase, FIKK family
    XP_001347445.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037281.1 Reference assembly

      Range
      656709..659027 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001347409.2 → XP_001347445.2  serine/threonine protein kinase, FIKK family [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001347445.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0L7KD84, Q8IJN3, W7JYJ9
      Conserved Domains (2) summary
      cd00180
      Location:370 → 487
      PKc; Catalytic domain of Protein Kinases
      cl21453
      Location:550 → 604
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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