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    PF3D7_1108400 casein kinase 2, alpha subunit [ Plasmodium falciparum 3D7 ]

    Gene ID: 810647, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1108400
    Gene description
    casein kinase 2, alpha subunit
    Locus tag
    PF3D7_1108400
    See related
    PlasmoDB:PF3D7_1108400; VEuPathDB:PF3D7_1108400
    Gene type
    protein coding
    RNA name
    casein kinase 2, alpha subunit
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1108400 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    1
    Sequence:
    Chromosome: 11; NC_037282.1 (365093..366100)

    Chromosome 11 - NC_037282.1Genomic Context describing neighboring genes Neighboring gene D-tyrosyl-tRNA(Tyr) deacylase Neighboring gene pterin-4a-carbinolamine dehydratase Neighboring gene succinyl-CoA synthetase alpha subunit, putative Neighboring gene endoplasmic reticulum-resident calcium binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037282.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis. Hitz E, et al. Commun Biol, 2021 Mar 12. PMID 33712726, Free PMC Article
    2. Malaria protein kinase CK2 (PfCK2) shows novel mechanisms of regulation. Graciotti M, et al. PLoS One, 2014. PMID 24658579, Free PMC Article
    3. Malaria Parasite-Infected Erythrocytes Secrete PfCK1, the Plasmodium Homologue of the Pleiotropic Protein Kinase Casein Kinase 1. Dorin-Semblat D, et al. PLoS One, 2015. PMID 26629826, Free PMC Article
    4. Functional analysis of protein kinase CK2 of the human malaria parasite Plasmodium falciparum. Holland Z, et al. Eukaryot Cell, 2009 Mar. PMID 19114502, Free PMC Article
    5. Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum. Bui HTN, et al. Sci Rep, 2019 Nov 13. PMID 31723180, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular vesicle HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein kinase CK2 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    casein kinase 2, alpha subunit
    XP_001347771.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037282.1 Reference assembly

      Range
      365093..366100
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001347735.1 → XP_001347771.1  casein kinase 2, alpha subunit [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001347771.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V6V9, A0A024VT17, A0A024W7C2, A0A024WQG2, A0A024X837, A0A0L1IF91, A0A0L7KIM3, A0A0L7M329, Q8IIR9, W4IF84, W4IRL1, W7EZX9, W7FX33, W7JB26, W7JTV7
      Conserved Domains (1) summary
      cd14132
      Location:24 → 328
      STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2
    Nucleotide Protein
    Heading Accession and Version

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