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    PF3D7_1209600 porphobilinogen deaminase [ Plasmodium falciparum 3D7 ]

    Gene ID: 811149, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1209600
    Gene description
    porphobilinogen deaminase
    Locus tag
    PF3D7_1209600
    See related
    PlasmoDB:PF3D7_1209600; VEuPathDB:PF3D7_1209600
    Gene type
    protein coding
    RNA name
    porphobilinogen deaminase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1209600 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    1
    Sequence:
    Chromosome: 12; NC_037284.1 (443680..444987)

    Chromosome 12 - NC_037284.1Genomic Context describing neighboring genes Neighboring gene cytosolic iron-sulfur protein assembly protein 1, putative Neighboring gene cGMP-specific 3',5'-cyclic phosphodiesterase alpha Neighboring gene conserved protein, unknown function Neighboring gene ATP synthase mitochondrial F1 complex assembly factor 1, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037284.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unique properties of Plasmodium falciparum porphobilinogen deaminase. Nagaraj VA, et al. J Biol Chem, 2008 Jan 4. PMID 17962188
    2. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article
    3. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables uroporphyrinogen-III synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within heme biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apicoplast HDA PubMed 
    located_in apicoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    porphobilinogen deaminase
    XP_001350505.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037284.1 Reference assembly

      Range
      443680..444987
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001350469.1 → XP_001350505.1  porphobilinogen deaminase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001350505.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V5H6, A0A024VPM6, A0A024W4T9, A0A024WMW4, A0A024X5G5, A0A0L1I342, A0A0L7KCM7, A0A0L7LYZ2, A8CBH8, Q8I5V3, W4IFD0, W4J273, W7F4T3, W7FW64, W7JKW0, W7JRC7
      Conserved Domains (1) summary
      cd13647
      Location:61 → 406
      PBP2_PBGD_2; An uncharacterized subgroup of the PBGD family; the type 2 periplasmic binding protein fold
    Nucleotide Protein
    Heading Accession and Version

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