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    PF3D7_1351600 glycerol kinase [ Plasmodium falciparum 3D7 ]

    Gene ID: 814234, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1351600
    Gene description
    glycerol kinase
    Locus tag
    PF3D7_1351600
    See related
    PlasmoDB:PF3D7_1351600; VEuPathDB:PF3D7_1351600
    Gene type
    protein coding
    RNA name
    glycerol kinase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1351600 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    1
    Sequence:
    Chromosome: 13; NC_004331.3 (2055216..2056721)

    Chromosome 13 - NC_004331.3Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium membrane protein, unknown function Neighboring gene 60S ribosomal protein L17, putative Neighboring gene ncRNA Neighboring gene inner membrane complex protein 1f, putative Neighboring gene conserved Plasmodium protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_004331.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reduced glycerol incorporation into phospholipids contributes to impaired intra-erythrocytic growth of glycerol kinase knockout Plasmodium falciparum parasites. Naidoo K, et al. Biochim Biophys Acta, 2013 Nov. PMID 23954205
    2. Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. Schnick C, et al. Mol Microbiol, 2009 Jan. PMID 19040641, Free PMC Article
    3. A network-based approach reveals novel invasion and Maurer's clefts-related proteins in Plasmodium falciparum. Das D, et al. Mol Omics, 2019 Dec 2. PMID 31631203

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Disruption of the P. falciparum glycerol kinase gene produced viable parasites.
      Title: Reduced glycerol incorporation into phospholipids contributes to impaired intra-erythrocytic growth of glycerol kinase knockout Plasmodium falciparum parasites.
    2. Blood stage malaria parasites do not utilize host-derived glycerol. Deletion of glycerol kinase had no effect on asexual parasite growth or gametocyte development or exflagellation.
      Title: Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Component Evidence Code Pubs
    located_in Maurer's cleft RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycerol kinase
    XP_001350228.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004331.3 Reference assembly

      Range
      2055216..2056721
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001350192.1 → XP_001350228.1  glycerol kinase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001350228.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V3H7, A0A024X2H8, A0A0L1IA10, A0A0L7KG61, A0A2I0BRQ5, Q8IDI4, W4ICB5, W4J1Z0, W7F640, W7FCI1, W7J796
      Conserved Domains (1) summary
      PTZ00294
      Location:1 → 498
      PTZ00294; glycerol kinase-like protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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