U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PF3D7_1420700 surface protein P113 [ Plasmodium falciparum 3D7 ]

    Gene ID: 811782, updated on 12-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PF3D7_1420700
    Gene description
    surface protein P113
    Locus tag
    PF3D7_1420700
    See related
    PlasmoDB:PF3D7_1420700; VEuPathDB:PF3D7_1420700
    Gene type
    protein coding
    RNA name
    surface protein P113
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PF3D7_1420700 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    2
    Sequence:
    Chromosome: 14; NC_037283.1 (860011..863080)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene protein GPR89, putative Neighboring gene pantothenate kinase 1, putative Neighboring gene dynein light chain, putative Neighboring gene mannose-1-phosphate guanyltransferase, putative

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture. Bullen HE, et al. Mol Microbiol, 2022 May. PMID 35403274, Free PMC Article
    2. The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site. Campeotto I, et al. mBio, 2020 Sep 8. PMID 32900802, Free PMC Article
    3. P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5. Galaway F, et al. Nat Commun, 2017 Feb 10. PMID 28186186, Free PMC Article
    4. Proteomic analysis of detergent-resistant membrane microdomains in trophozoite blood stage of the human malaria parasite Plasmodium falciparum. Yam XY, et al. Mol Cell Proteomics, 2013 Dec. PMID 24045696, Free PMC Article
    5. Myosin-like sequences in the malaria parasite Plasmodium falciparum bind human erythrocyte membrane protein 4.1. Lanzillotti R, et al. Haematologica, 2004 Oct. PMID 15477199

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site.
      Title: The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site.
    2. The reticulocyte binding protein homologue 5 N-terminal region (RH5Nt)-merozoite surface protein P113 (P113) interaction suggests a releasable mechanism for anchoring reticulocyte binding protein homologue 5 (RH5) to the merozoite surface.
      Title: P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5.
    3. The predicted transmembrane region may associate with band protein 4.1R by inserting into the RBC membrane. AA 801-869 contain a myosin-like motif.
      Title: Myosin-like sequences in the malaria parasite Plasmodium falciparum bind human erythrocyte membrane protein 4.1.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in symbiont-containing vacuole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in symbiont-containing vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    surface protein P113

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      860011..863080
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348338.1 → XP_001348374.1  surface protein P113 [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348374.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q8ILP3
      UniProtKB/TrEMBL
      A0A024WV89, A0A0L7M833, W4I9K9, W7JZA0
      Conserved Domains (1) summary
      COG5271
      Location:686 → 940
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials