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    PF3D7_0917900 heat shock protein 70 [ Plasmodium falciparum 3D7 ]

    Gene ID: 813455, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_0917900
    Gene description
    heat shock protein 70
    Locus tag
    PF3D7_0917900
    See related
    PlasmoDB:PF3D7_0917900; VEuPathDB:PF3D7_0917900
    Gene type
    protein coding
    RNA name
    heat shock protein 70
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_0917900 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    2
    Sequence:
    Chromosome: 9; NC_004330.2 (737985..740276)

    Chromosome 9 - NC_004330.2Genomic Context describing neighboring genes Neighboring gene GPN-loop GTPase, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene glideosome-associated protein 50 Neighboring gene cytochrome b5-like heme/steroid binding protein, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_004330.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Repurposing drugs to target the malaria parasite unfolding protein response. Chen Y, et al. Sci Rep, 2018 Jul 9. PMID 29985421, Free PMC Article
    2. Induction and localization of Plasmodium falciparum stress proteins related to the heat shock protein 70 family. Kumar N, et al. Mol Biochem Parasitol, 1991 Sep. PMID 1779989
    3. The endoplasmic reticulum chaperone PfGRP170 is essential for asexual development and is linked to stress response in malaria parasites. Kudyba HM, et al. Cell Microbiol, 2019 Sep. PMID 31087747, Free PMC Article
    4. Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics. Swearingen KE, et al. PLoS Pathog, 2016 Apr. PMID 27128092, Free PMC Article
    5. Food vacuole proteome of the malarial parasite Plasmodium falciparum. Lamarque M, et al. Proteomics Clin Appl, 2008 Sep. PMID 21136929

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to xenobiotic stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface HDA PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular vesicle HDA PubMed 
    located_in food vacuole HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    heat shock protein 70

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004330.2 Reference assembly

      Range
      737985..740276
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001352014.1 → XP_001352050.1  heat shock protein 70 [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001352050.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q05866, W7JXN5
      UniProtKB/TrEMBL
      A0A024V6C5, A0A024W9D7, A0A024WSR3, A0A024X5H6, A0A0L0CWG5, A0A0L1I897, A0A0L7K9H1, A0A2I0BST9, Q8I2X4, W4IHJ6, W4J0F1, W7F8F2, W7FJD1
      Conserved Domains (1) summary
      PTZ00009
      Location:27 → 643
      PTZ00009; heat shock 70 kDa protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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