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    Snord115 small nucleolar RNA, C/D Box 115 cluster [ Mus musculus (house mouse) ]

    Gene ID: 493919, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Snord115provided by MGI
    Official Full Name
    small nucleolar RNA, C/D Box 115 clusterprovided by MGI
    Primary source
    MGI:MGI:3510326
    Gene type
    other
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MBII-52
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    chromosome: 7

    Bibliography

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    Related articles in PubMed

    1. Deleting Snord115 genes in mice remodels monoaminergic systems activity in the brain toward cortico-subcortical imbalances. Marty V, et al. Hum Mol Genet, 2023 Jan 6. PMID 35951020
    2. The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing. Kishore S, et al. Hum Mol Genet, 2010 Apr 1. PMID 20053671, Free PMC Article
    3. Reassessment of the involvement of Snord115 in the serotonin 2c receptor pathway in a genetically relevant mouse model. Hebras J, et al. Elife, 2020 Oct 5. PMID 33016258, Free PMC Article
    4. Neuronal differentiation induces SNORD115 expression and is accompanied by post-transcriptional changes of serotonin receptor 2c mRNA. Bratkovič T, et al. Sci Rep, 2018 Mar 23. PMID 29572515, Free PMC Article
    5. The SNORD115 (H/MBII-52) and SNORD116 (H/MBII-85) gene clusters at the imprinted Prader-Willi locus generate canonical box C/D snoRNAs. Bortolin-Cavaillé ML, et al. Nucleic Acids Res, 2012 Aug. PMID 22495932, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Deleting Snord115 genes in mice remodels monoaminergic systems activity in the brain toward cortico-subcortical imbalances.
      Title: Deleting Snord115 genes in mice remodels monoaminergic systems activity in the brain toward cortico-subcortical imbalances.
    2. Both SNORD115 and 5ht2c were upregulated upon neuronal commitment.
      Title: Neuronal differentiation induces SNORD115 expression and is accompanied by post-transcriptional changes of serotonin receptor 2c mRNA.
    3. Lacking expression of mbii-52 increased RNA editing, but not alternative splicing of the 5htr2c pre-RNA.
      Title: Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Other Names

    • snoRNA MBII-52
    Nucleotide Protein
    Heading Accession and Version

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