Bin1 bridging integrator 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Bin1provided by MGI
Official Full Name: bridging integrator 1provided by MGI
Primary source: MGI:MGI:108092
See related: Ensembl:ENSMUSG00000024381 AllianceGenome:MGI:108092
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: ALP-1; Amphl; SH3P9; BRAMP-2
Summary: Enables aspartic-type endopeptidase inhibitor activity; signaling adaptor activity; and tau protein binding activity. Involved in several processes, including negative regulation of amyloid precursor protein catabolic process; negative regulation of cation transmembrane transport; and regulation of heart contraction. Acts upstream of or within muscle cell differentiation. Located in several cellular components, including T-tubule; dendrite; and nuclear envelope. Is active in glutamatergic synapse; postsynapse; and presynapse. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; heart; and musculature. Human ortholog(s) of this gene implicated in breast carcinoma; centronuclear myopathy 2; and prostate adenocarcinoma. Orthologous to human BIN1 (bridging integrator 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in cerebellum adult (RPKM 72.8), cortex adult (RPKM 65.7) and 25 other tissues See more
Orthologs: human all
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Genomic context

Location:: 18 B1; 18 18.01 cM

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	18	NC_000084.7 (32509671..32568793)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	18	NC_000084.6 (32376618..32435740)

Chromosome 18 - NC_000084.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation.
Title: BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation.
BIN1 knockdown rescues systolic dysfunction in aging male mouse hearts.
Title: BIN1 knockdown rescues systolic dysfunction in aging male mouse hearts.
Bridging integrator 1 fragment accelerates tau aggregation and propagation by enhancing clathrin-mediated endocytosis in mice.
Title: Bridging integrator 1 fragment accelerates tau aggregation and propagation by enhancing clathrin-mediated endocytosis in mice.
Tamoxifen improves muscle structure and function of Bin1- and Dnm2-related centronuclear myopathies.
Title: Tamoxifen improves muscle structure and function of Bin1- and Dnm2-related centronuclear myopathies.
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes.
Title: BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes.
Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model.
Title: Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model.
Polycystin-1 Is a Crucial Regulator of BIN1 Expression and T-Tubule Remodeling Associated with the Development of Dilated Cardiomyopathy.
Title: Polycystin-1 Is a Crucial Regulator of BIN1 Expression and T-Tubule Remodeling Associated with the Development of Dilated Cardiomyopathy.
BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
Title: BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
Mice with muscle-specific deletion of Bin1 recapitulate centronuclear myopathy and acute downregulation of dynamin 2 improves their phenotypes.
Title: Mice with muscle-specific deletion of Bin1 recapitulate centronuclear myopathy and acute downregulation of dynamin 2 improves their phenotypes.
Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle.
Title: Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle.

Submit: New GeneRIF Correction See all GeneRIFs (40)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (7) 1 citation
Targeted (4) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

PMC156129P1 (e-PCR)
- UniSTS:271363

PMC156129P2 (e-PCR)
- UniSTS:271364

RH141034 (e-PCR)
- UniSTS:223034

U86405 (e-PCR)
- UniSTS:181108

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables GTPase binding	IEA Inferred from Electronic Annotation more info
enables GTPase binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase binding	ISO Inferred from Sequence Orthology more info
enables actin filament binding	IEA Inferred from Electronic Annotation more info
enables actin filament binding	ISO Inferred from Sequence Orthology more info
enables aspartic-type endopeptidase inhibitor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables aspartic-type endopeptidase inhibitor activity	ISO Inferred from Sequence Orthology more info
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info
enables protease binding	IEA Inferred from Electronic Annotation more info
enables protease binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein-containing complex binding	ISO Inferred from Sequence Orthology more info
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info
enables protein-folding chaperone binding	ISO Inferred from Sequence Orthology more info
enables signaling adaptor activity	IDA Inferred from Direct Assay more info	PubMed
enables tau protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables tau protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables tau protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in T-tubule organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in T-tubule organization	ISO Inferred from Sequence Orthology more info
involved_in endosome to lysosome transport	IEA Inferred from Electronic Annotation more info
involved_in endosome to lysosome transport	ISO Inferred from Sequence Orthology more info
involved_in lipid tube assembly	ISO Inferred from Sequence Orthology more info
involved_in lipid tube assembly	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within muscle cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of amyloid-beta formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of amyloid-beta formation	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of potassium ion transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of ventricular cardiac muscle cell action potential	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nucleus localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nucleus organization	IEA Inferred from Electronic Annotation more info
involved_in nucleus organization	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of actin filament polymerization	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of apoptotic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of astrocyte differentiation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of astrocyte differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of endocytosis	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of endocytosis	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell cycle process	ISO Inferred from Sequence Orthology more info
involved_in regulation of heart rate by cardiac conduction	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of neuron differentiation	ISO Inferred from Sequence Orthology more info
involved_in regulation of neuron differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to lipopolysaccharide	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic vesicle endocytosis	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic vesicle endocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in synaptic vesicle endocytosis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in I band	ISO Inferred from Sequence Orthology more info
located_in I band	ISS Inferred from Sequence or Structural Similarity more info
part_of RNA polymerase II transcription repressor complex	ISO Inferred from Sequence Orthology more info
located_in T-tubule	IDA Inferred from Direct Assay more info	PubMed
located_in T-tubule	ISO Inferred from Sequence Orthology more info
located_in T-tubule	ISS Inferred from Sequence or Structural Similarity more info
located_in Z disc	ISO Inferred from Sequence Orthology more info
located_in Z disc	ISS Inferred from Sequence or Structural Similarity more info
located_in axon	IDA Inferred from Direct Assay more info	PubMed
located_in axon	ISO Inferred from Sequence Orthology more info
located_in axon	ISS Inferred from Sequence or Structural Similarity more info
located_in axon initial segment	ISO Inferred from Sequence Orthology more info
located_in axon initial segment	ISS Inferred from Sequence or Structural Similarity more info
located_in axon terminus	IEA Inferred from Electronic Annotation more info
located_in axon terminus	ISO Inferred from Sequence Orthology more info
located_in cerebellar mossy fiber	IEA Inferred from Electronic Annotation more info
located_in cerebellar mossy fiber	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
colocalizes_with cytoskeleton	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in extrinsic component of synaptic vesicle membrane	IEA Inferred from Electronic Annotation more info
is_active_in extrinsic component of synaptic vesicle membrane	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in glutamatergic synapse	IMP Inferred from Mutant Phenotype more info	PubMed
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
part_of lipid tube	ISO Inferred from Sequence Orthology more info
part_of lipid tube	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in microtubule	ISS Inferred from Sequence or Structural Similarity more info
located_in node of Ranvier	ISO Inferred from Sequence Orthology more info
located_in node of Ranvier	ISS Inferred from Sequence or Structural Similarity more info
located_in nuclear envelope	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in postsynapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in presynapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in synapse	EXP Inferred from Experiment more info	PubMed
is_active_in synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in synaptic vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in synaptic vesicle	ISO Inferred from Sequence Orthology more info
located_in varicosity	IEA Inferred from Electronic Annotation more info
located_in varicosity	ISO Inferred from Sequence Orthology more info
located_in vesicle	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: myc box-dependent-interacting protein 1

Names: SH3 domain-containing protein 9; amphiphysin 2; amphiphysin II; amphiphysin-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001083334.1 → NP_001076803.1 myc box-dependent-interacting protein 1 isoform 2

See identical proteins and their annotated locations for NP_001076803.1

Status: VALIDATED

Source sequence(s)

AI840452, BC065160, CJ121020

Consensus CDS

CCDS37755.1

UniProtKB/TrEMBL

Q6P1B9

Related

ENSMUSP00000089590.6, ENSMUST00000091967.13

Conserved Domains (2) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:405 → 476

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
NM_001360876.1 → NP_001347805.1 myc box-dependent-interacting protein 1 isoform 3

Status: VALIDATED

Source sequence(s)

AC126026

Conserved Domains (2) summary

cd07611
Location:31 → 272

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:480 → 551

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
NM_009668.2 → NP_033798.1 myc box-dependent-interacting protein 1 isoform 1

See identical proteins and their annotated locations for NP_033798.1

Status: VALIDATED

Source sequence(s)

AI840452, AW496330, BQ573238, BU707946, CF732768, CJ121020, CO426739

Consensus CDS

CCDS29119.1

UniProtKB/Swiss-Prot

O08539, Q62434

Related

ENSMUSP00000025239.8, ENSMUST00000025239.9

Conserved Domains (4) summary

cd07611
Location:31 → 272

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:516 → 587

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl26247
Location:400 → 473

DNA_pol3_delta2; DNA polymerase III, delta subunit

cl26386
Location:316 → 490

DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000084.7 Reference GRCm39 C57BL/6J

Range

32509671..32568793

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030250491.1 → XP_030106351.1 myc box-dependent-interacting protein 1 isoform X7

Conserved Domains (2) summary

cd07611
Location:31 → 272

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:480 → 551

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_017317916.3 → XP_017173405.1 myc box-dependent-interacting protein 1 isoform X10

Conserved Domains (2) summary

cd12139
Location:436 → 507

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl12013
Location:31 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006525987.4 → XP_006526050.1 myc box-dependent-interacting protein 1 isoform X13

Conserved Domains (2) summary

cd12139
Location:412 → 483

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl12013
Location:31 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006525978.5 → XP_006526041.1 myc box-dependent-interacting protein 1 isoform X1

Conserved Domains (4) summary

cd07611
Location:31 → 272

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

PRK14959
Location:415 → 488

PRK14959; DNA polymerase III subunits gamma and tau; Provisional

cd12139
Location:531 → 602

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

PRK12323
Location:331 → 505

PRK12323; DNA polymerase III subunit gamma/tau
XM_006525981.5 → XP_006526044.1 myc box-dependent-interacting protein 1 isoform X4

Conserved Domains (2) summary

cd07611
Location:31 → 272

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:495 → 566

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_006525984.5 → XP_006526047.1 myc box-dependent-interacting protein 1 isoform X8

Conserved Domains (2) summary

cd12139
Location:451 → 522

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl12013
Location:31 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006525985.5 → XP_006526048.1 myc box-dependent-interacting protein 1 isoform X11

Conserved Domains (2) summary

cd12139
Location:427 → 498

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl12013
Location:31 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006525988.5 → XP_006526051.1 myc box-dependent-interacting protein 1 isoform X14

Conserved Domains (2) summary

cd12139
Location:408 → 479

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl12013
Location:31 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006525990.5 → XP_006526053.1 myc box-dependent-interacting protein 1 isoform X16

Conserved Domains (2) summary

cd12139
Location:384 → 455

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl12013
Location:31 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006525989.5 → XP_006526052.1 myc box-dependent-interacting protein 1 isoform X15

Conserved Domains (2) summary

cd12139
Location:393 → 464

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl12013
Location:31 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006525992.5 → XP_006526055.1 myc box-dependent-interacting protein 1 isoform X19

Conserved Domains (2) summary

cd12139
Location:369 → 440

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

cl12013
Location:31 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006525980.5 → XP_006526043.1 myc box-dependent-interacting protein 1 isoform X3

Conserved Domains (4) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

PRK14959
Location:384 → 457

PRK14959; DNA polymerase III subunits gamma and tau; Provisional

cd12139
Location:500 → 571

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

PRK12323
Location:300 → 474

PRK12323; DNA polymerase III subunit gamma/tau
XM_006525986.5 → XP_006526049.1 myc box-dependent-interacting protein 1 isoform X12

Conserved Domains (2) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:420 → 491

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_006525991.5 → XP_006526054.1 myc box-dependent-interacting protein 1 isoform X18

UniProtKB/TrEMBL

A0AAQ4VMS1

Related

ENSMUSP00000159972.1, ENSMUST00000249875.1

Conserved Domains (2) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:377 → 448

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_006525994.5 → XP_006526057.1 myc box-dependent-interacting protein 1 isoform X21

Conserved Domains (2) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:353 → 424

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_006525982.5 → XP_006526045.1 myc box-dependent-interacting protein 1 isoform X6

Conserved Domains (4) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

PRK14959
Location:369 → 442

PRK14959; DNA polymerase III subunits gamma and tau; Provisional

cd12139
Location:485 → 556

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

PRK12323
Location:285 → 459

PRK12323; DNA polymerase III subunit gamma/tau
XM_030250493.2 → XP_030106353.1 myc box-dependent-interacting protein 1 isoform X9

Conserved Domains (2) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:449 → 520

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_017317917.3 → XP_017173406.1 myc box-dependent-interacting protein 1 isoform X17

Conserved Domains (2) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:381 → 452

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_006525993.4 → XP_006526056.1 myc box-dependent-interacting protein 1 isoform X20

See identical proteins and their annotated locations for XP_006526056.1

UniProtKB/Swiss-Prot

O08539

Related

ENSMUSP00000157259.2, ENSMUST00000234857.2

Conserved Domains (2) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:362 → 433

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_006525995.4 → XP_006526058.1 myc box-dependent-interacting protein 1 isoform X22

UniProtKB/TrEMBL

A0A3Q4EBK4

Related

ENSMUSP00000156976.2, ENSMUST00000234496.2

Conserved Domains (2) summary

cd07611
Location:31 → 241

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:338 → 409

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2
XM_006525979.3 → XP_006526042.1 myc box-dependent-interacting protein 1 isoform X2

Conserved Domains (4) summary

cd07611
Location:26 → 267

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

PRK14959
Location:410 → 483

PRK14959; DNA polymerase III subunits gamma and tau; Provisional

cd12139
Location:526 → 597

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

PRK12323
Location:326 → 500

PRK12323; DNA polymerase III subunit gamma/tau
XM_030250490.2 → XP_030106350.1 myc box-dependent-interacting protein 1 isoform X5

Conserved Domains (4) summary

cd07611
Location:26 → 236

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

PRK14959
Location:379 → 452

PRK14959; DNA polymerase III subunits gamma and tau; Provisional

cd12139
Location:495 → 566

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2

PRK12323
Location:295 → 469

PRK12323; DNA polymerase III subunit gamma/tau
XM_030250497.2 → XP_030106357.1 myc box-dependent-interacting protein 1 isoform X23

Conserved Domains (2) summary

cd07611
Location:26 → 236

BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II

cd12139
Location:333 → 404

SH3_Bin1; Src Homology 3 domain of Bridging integrator 1 (Bin1), also called Amphiphysin-2