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    SNR128 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 9164909, updated on 2-Nov-2024

    Summary

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    Official Symbol
    SNR128
    Primary source
    SGD:S000006508
    Locus tag
    YNCJ0003C
    See related
    AllianceGenome:SGD:S000006508
    Gene type
    ncRNA
    RNA name
    snoRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables rRNA binding activity. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in cytoplasm and nucleolus. Part of box C/D methylation guide snoRNP complex. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See SNR128 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (139566..139691, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Sna3p Neighboring gene SCF ubiquitin ligase complex subunit DAS1 Neighboring gene ncRNA Neighboring gene DNA-directed RNA polymerase I subunit RPA34

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Accumulation of U14 small nuclear RNA in Saccharomyces cerevisiae requires box C, box D, and a 5', 3' terminal stem. Huang GM, et al. Mol Cell Biol, 1992 Oct. PMID 1406634, Free PMC Article
    2. U14 function in Saccharomyces cerevisiae can be provided by large deletion variants of yeast U14 and hybrid mouse-yeast U14 RNAs. Li D, et al. EMBO J, 1992 Feb. PMID 1537342, Free PMC Article
    3. Identification of essential elements in U14 RNA of Saccharomyces cerevisiae. Jarmolowski A, et al. EMBO J, 1990 Dec. PMID 2265615, Free PMC Article
    4. Depletion of U14 small nuclear RNA (snR128) disrupts production of 18S rRNA in Saccharomyces cerevisiae. Li HD, et al. Mol Cell Biol, 1990 Mar. PMID 2406561, Free PMC Article
    5. U14 base-pairs with 18S rRNA: a novel snoRNA interaction required for rRNA processing. Liang WQ, et al. Genes Dev, 1995 Oct 1. PMID 7557394

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • C/D box small nucleolar RNA (snoRNA); referred to as U14; essential gene required for cleavage of 35S primary rRNA transcript to release the precursor to the 18S rRNA; guides 2'-O-methylation of small subunit (SSU) rRNA at position C414

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables rRNA 2'-O-ribose methylation guide activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables rRNA binding IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables rRNA binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA methylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of box C/D methylation guide snoRNP complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of box C/D methylation guide snoRNP complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      139566..139691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_132193.1 RNA Sequence

      Status: REVIEWED

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