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    RDN25-1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 9164935, updated on 11-Sep-2024

    Summary

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    Official Symbol
    RDN25-1
    Primary source
    SGD:S000006484
    Locus tag
    YNCL0012C
    See related
    AllianceGenome:SGD:S000006484
    Gene type
    rRNA
    RNA name
    25S ribosomal RNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be a structural constituent of ribosome. Involved in protein folding; regulation of translational fidelity; and translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RDN25-1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (451786..455181, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene tRNA-Gln Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene Tar1p Neighboring gene miscRNA Neighboring gene 5.8S ribosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. rRNA expansion segment 27Lb modulates the factor recruitment capacity of the yeast ribosome and shapes the proteome. Shankar V, et al. Nucleic Acids Res, 2020 Apr 6. PMID 31960048, Free PMC Article
    2. Ricin uses arginine 235 as an anchor residue to bind to P-proteins of the ribosomal stalk. Zhou Y, et al. Sci Rep, 2017 Feb 23. PMID 28230053, Free PMC Article
    3. Random mutagenesis of yeast 25S rRNA identify bases critical for 60S subunit structural integrity and function. Nemoto N, et al. Translation (Austin), 2013. PMID 26824023, Free PMC Article
    4. Major centers of motion in the large ribosomal RNAs. Paci M, et al. Nucleic Acids Res, 2015 May 19. PMID 25870411, Free PMC Article
    5. Interaction between 25S rRNA A loop and eukaryotic translation initiation factor 5B promotes subunit joining and ensures stringent AUG selection. Hiraishi H, et al. Mol Cell Biol, 2013 Sep. PMID 23836883, Free PMC Article

    See all (71) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • 25S ribosomal RNA (25S rRNA); component of the large (60S) ribosomal subunit; encoded in the rDNA repeat (RDN1) as part of the 35S primary transcript; formed by endonucleolytic cleavage at the C2 site of internal transcribed spacer 2 (ITS2)

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of translational fidelity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translational elongation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translational initiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      451786..455181 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_132209.1 RNA Sequence

      Status: REVIEWED

    Gene LinkOut

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