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    BNS1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853145, updated on 22-Aug-2024

    Summary

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    Official Symbol
    BNS1
    Primary source
    FungiDB:YGR230W
    Locus tag
    YGR230W
    See related
    SGD:S000003462; AllianceGenome:SGD:S000003462; VEuPathDB:YGR230W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in meiotic cell cycle and negative regulation of protein localization to nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See BNS1 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (951894..952307)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Oto1p Neighboring gene Smi1p Neighboring gene prohibitin subunit PHB2 Neighboring gene Nas6p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of the polo kinase Cdc5 in controlling Cdc14 localization. Visintin R, et al. Mol Biol Cell, 2003 Nov. PMID 14551257, Free PMC Article
    2. Cdc14 and condensin control the dissolution of cohesin-independent chromosome linkages at repeated DNA. D'Amours D, et al. Cell, 2004 May 14. PMID 15137939
    3. A mechanism for chromosome segregation sensing by the NoCut checkpoint. Mendoza M, et al. Nat Cell Biol, 2009 Apr. PMID 19270692
    4. Genetic and biochemical characterization of the yeast spo12 protein. Grether ME, et al. Mol Biol Cell, 1999 Nov. PMID 10564265, Free PMC Article
    5. Asymmetry of the budding yeast Tem1 GTPase at spindle poles is required for spindle positioning but not for mitotic exit. Scarfone I, et al. PLoS Genet, 2015 Feb. PMID 25658911, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in meiotic cell cycle IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in negative regulation of protein localization to nucleolus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Bns1p
    NP_011746.3
    • hypothetical protein; FEAR network component that partially overlaps the function of SPO12 in promoting Cdc14p release from the nucleolus during early mitotic anaphase and mitotic exit; overexpression partially suppresses the meiotic defect of spo12; BNS1 has a paralog, SPO12, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      951894..952307
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181359.3 → NP_011746.3  TPA: Bns1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011746.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VV10, P50084
      UniProtKB/TrEMBL
      A6ZUN8, B3LI10, B5VJG8, C7GNJ9, C8Z9C2, G2WEV6, N1P654
      Conserved Domains (1) summary
      pfam05032
      Location:89 → 121
      Spo12; Spo12 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P50084.1

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