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    TDA10 putative ATP-dependent kinase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853119, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TDA10
    Official Full Name
    putative ATP-dependent kinase
    Primary source
    SGD:S000003437
    Locus tag
    YGR205W
    See related
    AllianceGenome:SGD:S000003437; FungiDB:YGR205W; VEuPathDB:YGR205W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables ATP binding activity. Predicted to be involved in phosphorylation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See TDA10 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (909213..910085)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Neighboring gene uncharacterized protein Neighboring gene ubiquitin-binding ESCRT-I subunit protein MVB12 Neighboring gene Cir1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase. Li de La Sierra-Gallay I, et al. Proteins, 2004 Mar 1. PMID 14997573
    2. Sequencing of a 17.6 kb segment on the right arm of yeast chromosome VII reveals 12 ORFs, including CCT, ADE3 and TR-I genes, homologues of the yeast PMT and EF1G genes, of the human and bacterial electron-transferring flavoproteins (beta-chain) and of the Escherichia coli phosphoserine phosphohydrolase, and five new ORFs. Guerreiro P, et al. Yeast, 1996 Mar 15. PMID 8904340
    3. Pex19 is involved in importing dually targeted tail-anchored proteins to both mitochondria and peroxisomes. Cichocki BA, et al. Traffic, 2018 Oct. PMID 30033679
    4. Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Reid RJ, et al. Genome Res, 2011 Mar. PMID 21173034, Free PMC Article
    5. The S. cerevisiae m6A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts. Scutenaire J, et al. Nucleic Acids Res, 2023 Jan 25. PMID 35934316, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative ATP-dependent kinase
    NP_011721.3
    • ATP-binding hypothetical protein; crystal structure resembles that of E.coli pantothenate kinase and other small kinases; null mutant is sensitive to expression of the top1-T722A allele

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      909213..910085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181334.3 → NP_011721.3  TPA: putative ATP-dependent kinase [Saccharomyces cerevisiae S288C]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUY8, P42938
      UniProtKB/TrEMBL
      A6ZUL6, B3LI31, B5VJE7, C7GRN8, C8Z998, G2WET4, N1P3Y7
      Conserved Domains (1) summary
      COG4240
      Location:1 → 287
      Tda10; Pantothenate kinase-related protein Tda10 (topoisomerase I damage affected protein) [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42938.1

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