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    AGA2 Aga2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852851, updated on 17-May-2024

    Summary

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    Gene symbol
    AGA2
    Gene description
    Aga2p
    Primary source
    FungiDB:YGL032C
    Locus tag
    YGL032C
    See related
    SGD:S000003000; AllianceGenome:SGD:S000003000; VEuPathDB:YGL032C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables cell adhesion molecule binding activity. Involved in agglutination involved in conjugation with cellular fusion. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See AGA2 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (436570..436833, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Hop2p Neighboring gene ribosomal 60S subunit protein L24A Neighboring gene ribosomal 60S subunit protein L30

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NY-ESO-1 protein glycosylated by yeast induces enhanced immune responses. Wadle A, et al. Yeast, 2010 Nov. PMID 20672253
    2. [Cell surface display of Yarrowia lipolytica lipase Lip2 in Saccharomyces cerevisiae with a-agglutinin as carrier protein]. Liu W, et al. Wei Sheng Wu Xue Bao, 2008 Nov. PMID 19149173
    3. Purification and characterization of the inducible a agglutinin of Saccharomyces cerevisiae. Watzele M, et al. EMBO J, 1988 May. PMID 3044782, Free PMC Article
    4. Saccharomyces cerevisiae a- and alpha-agglutinin: characterization of their molecular interaction. Cappellaro C, et al. EMBO J, 1991 Dec. PMID 1756718, Free PMC Article
    5. An efficient and simple method to increase the level of displayed protein on the yeast cell surface. Zhao JZ, et al. J Microbiol Methods, 2017 Apr. PMID 28188810

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in agglutination involved in conjugation with cellular fusion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in agglutination involved in conjugation with cellular fusion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type cell wall IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Aga2p
    NP_011483.3
    • Adhesion subunit of a-agglutinin of a-cells; C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      436570..436833 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180897.3 → NP_011483.3  TPA: Aga2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011483.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUA6, P32781
      UniProtKB/TrEMBL
      A0A8H4C228, A6ZUW2, B3LIP4, C7GT49, C8Z8L0, G2WE62, N1P3P2
      Conserved Domains (1) summary
      pfam17366
      Location:27 → 87
      AGA2; A-agglutinin-binding subunit Aga2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32781.1

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