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    MRPL28 mitochondrial 54S ribosomal protein YmL28 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852073, updated on 17-May-2024

    Summary

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    Gene symbol
    MRPL28
    Gene description
    mitochondrial 54S ribosomal protein YmL28
    Primary source
    FungiDB:YDR462W
    Locus tag
    YDR462W
    See related
    SGD:S000002870; AllianceGenome:SGD:S000002870; VEuPathDB:YDR462W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    mL40
    Summary
    A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See MRPL28 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1386073..1386516)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene mating pheromone a Neighboring gene Cmi8p Neighboring gene Stp1p Neighboring gene Spp41p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic differences between Candida glabrata and Saccharomyces cerevisiae around the MRPL28 and GCN3 loci. Walsh DW, et al. Yeast, 2002 Aug. PMID 12125055
    2. MrpL35, a mitospecific component of mitoribosomes, plays a key role in cytochrome c oxidase assembly. Box JM, et al. Mol Biol Cell, 2017 Nov 15. PMID 28931599, Free PMC Article
    3. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Kitakawa M, et al. Eur J Biochem, 1997 Apr 15. PMID 9151978
    4. Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis. Alamgir M, et al. BMC Genomics, 2008 Dec 3. PMID 19055778, Free PMC Article
    5. The DEAD-box helicase Mss116 plays distinct roles in mitochondrial ribogenesis and mRNA-specific translation. De Silva D, et al. Nucleic Acids Res, 2017 Jun 20. PMID 28520979, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mitochondrial translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL28
    NP_010750.1
    • Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1386073..1386516
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180770.1 → NP_010750.1  TPA: mitochondrial 54S ribosomal protein YmL28 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010750.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT87, P36527, Q00949
      UniProtKB/TrEMBL
      A0A6A5Q320, A6ZZ53, B3LFK2, C7GKQ4, C8Z621, G2WBJ3, N1P7J9
      Conserved Domains (1) summary
      pfam09812
      Location:23 → 137
      MRP-L28; Mitochondrial ribosomal protein L28
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36527.2

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