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    MRPL35 mitochondrial 54S ribosomal protein YmL35 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851921, updated on 9-Jun-2024

    Summary

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    Gene symbol
    MRPL35
    Gene description
    mitochondrial 54S ribosomal protein YmL35
    Primary source
    FungiDB:YDR322W
    Locus tag
    YDR322W
    See related
    SGD:S000002730; AllianceGenome:SGD:S000002730; VEuPathDB:YDR322W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    mL38
    Summary
    A structural constituent of ribosome. Involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL38 (mitochondrial ribosomal protein L38). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See MRPL35 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1110589..1111692)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Dad4p Neighboring gene asparaginase ASP1 Neighboring gene F1F0 ATP synthase subunit e Neighboring gene phosphatidylinositol-3-phosphate binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MrpL35, a mitospecific component of mitoribosomes, plays a key role in cytochrome c oxidase assembly. Box JM, et al. Mol Biol Cell, 2017 Nov 15. PMID 28931599, Free PMC Article
    2. Proteasome Impairment Induces Recovery of Mitochondrial Membrane Potential and an Alternative Pathway of Mitochondrial Fusion. Shirozu R, et al. Mol Cell Biol, 2016 Jan 15. PMID 26552703, Free PMC Article
    3. The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans. Aerts AM, et al. Front Microbiol, 2011. PMID 21993350, Free PMC Article
    4. Yeast mitochondrial RNase P, RNase Z and the RNA degradosome are part of a stable supercomplex. Daoud R, et al. Nucleic Acids Res, 2012 Feb. PMID 22034500, Free PMC Article
    5. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Kitakawa M, et al. Eur J Biochem, 1997 Apr 15. PMID 9151978

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL35
    NP_010608.1
    • Mitochondrial ribosomal protein of the large subunit; involved together with Mrp7p in assembly of cytochrome c oxidase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1110589..1111692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180630.1 → NP_010608.1  TPA: mitochondrial 54S ribosomal protein YmL35 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010608.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSV4, Q06678
      UniProtKB/TrEMBL
      A0A8H8UNM1, A6ZYS4, B3LFX5, C7GWM0, N1P760
      Conserved Domains (1) summary
      cd00866
      Location:178 → 341
      PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06678.1

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