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    CBP6 Cbp6p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852417, updated on 2-Nov-2024

    Summary

    Official Symbol
    CBP6
    Official Full Name
    Cbp6p
    Primary source
    SGD:S000000324
    Locus tag
    YBR120C
    See related
    AllianceGenome:SGD:S000000324; FungiDB:YBR120C; VEuPathDB:YBR120C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables ribosome binding activity. Involved in mitochondrial respiratory chain complex III assembly and positive regulation of mitochondrial translation. Located in mitochondrial ribosome. Part of Cbp3p-Cbp6 complex. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See CBP6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (480435..480923, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene translation elongation factor EF-1 alpha Neighboring gene Mud1p Neighboring gene glycine--tRNA ligase Neighboring gene mitochondrial 54S ribosomal protein YmL36

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribosome binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Cbp3p-Cbp6 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Cbp3p-Cbp6 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Cbp3p-Cbp6 complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    located_in mitochondrial ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Cbp6p
    NP_009678.3
    • Mitochondrial protein required for translation of the COB mRNA; forms a complex with Cbp3p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex; Cbp3p-Cbp6p complex is sequestered if assembly of Complex III is blocked, downregulating COB mRNA translation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      480435..480923 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178468.3NP_009678.3  TPA: Cbp6p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009678.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQB8, E9P8V5, P07253
      UniProtKB/TrEMBL
      A6ZL65, B3LN35, B5VE80, C7GY05, G2W9C5, N1P6N6