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    MRPL16 mitochondrial 54S ribosomal protein YmL47 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852242, updated on 17-May-2024

    Summary

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    Gene symbol
    MRPL16
    Gene description
    mitochondrial 54S ribosomal protein YmL47
    Primary source
    FungiDB:YBL038W
    Locus tag
    YBL038W
    See related
    SGD:S000000134; AllianceGenome:SGD:S000000134; VEuPathDB:YBL038W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RML16; uL16m
    Summary
    A structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL16 (mitochondrial ribosomal protein L16). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See MRPL16 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (146187..146885)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Min6p Neighboring gene CTP synthase URA7 Neighboring gene Apl3p Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the yeast nuclear gene for the mitochondrial homologue of bacterial ribosomal protein L16. Pan C, et al. Nucleic Acids Res, 1995 Sep 25. PMID 7478995, Free PMC Article
    2. Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. Kursu VA, et al. Mol Microbiol, 2013 Nov. PMID 24102902, Free PMC Article
    3. Genomewide analysis reveals novel pathways affecting endoplasmic reticulum homeostasis, protein modification and quality control. Copic A, et al. Genetics, 2009 Jul. PMID 19433630, Free PMC Article
    4. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Kitakawa M, et al. Eur J Biochem, 1997 Apr 15. PMID 9151978
    5. Functional discovery via a compendium of expression profiles. Hughes TR, et al. Cell, 2000 Jul 7. PMID 10929718

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL47
    NP_009515.1
    • Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetic lethality with hac1 mutation suggests a possible role in synthesis of precursors for protein glycosylation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      146187..146885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178278.1 → NP_009515.1  TPA: mitochondrial 54S ribosomal protein YmL47 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009515.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VPW1, P38064, Q07216
      UniProtKB/TrEMBL
      A0A6A5Q1J7, G2W8X0, N1P9Q5
      Conserved Domains (1) summary
      cl00353
      Location:42 → 174
      Ribosomal_L16_L10e; L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with the 30S subunit, ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38064.1

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