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    MRPL40 mitochondrial 54S ribosomal protein YmL40 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855930, updated on 17-May-2024

    Summary

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    Gene symbol
    MRPL40
    Gene description
    mitochondrial 54S ribosomal protein YmL40
    Primary source
    FungiDB:YPL173W
    Locus tag
    YPL173W
    See related
    SGD:S000006094; AllianceGenome:SGD:S000006094; VEuPathDB:YPL173W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uL24m
    Summary
    A structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL24 (mitochondrial ribosomal protein L24). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See MRPL40 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (223143..224036)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase SPT14 Neighboring gene Nip100p Neighboring gene protoheme IX farnesyltransferase Neighboring gene NADPH dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The DEAD box protein Mrh4 functions in the assembly of the mitochondrial large ribosomal subunit. De Silva D, et al. Cell Metab, 2013 Nov 5. PMID 24206665, Free PMC Article
    2. Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly. Jia L, et al. Eukaryot Cell, 2009 Nov. PMID 19783770, Free PMC Article
    3. High levels of the mitochondrial large ribosomal subunit protein 40 prevent loss of mitochondrial DNA in null mmf1 Saccharomyces cerevisiae cells. Accardi R, et al. Yeast, 2004 May. PMID 15164357
    4. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. Gruschke S, et al. J Biol Chem, 2010 Jun 18. PMID 20404317, Free PMC Article
    5. Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria. Kaur J, et al. EMBO Rep, 2011 Sep 1. PMID 21779004, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MrpL40, a large ribosomal subunit component, is physically interact with Oxa1.
      Title: Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in intracellular organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL40
    NP_015152.1
    • Mitochondrial ribosomal protein of the large subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      223143..224036
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183987.1 → NP_015152.1  TPA: mitochondrial 54S ribosomal protein YmL40 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015152.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3J5, P36534, Q6B277
      UniProtKB/TrEMBL
      A0A6A5Q0S7, A6ZW80, B3LKQ5, B5VSZ8, C8ZIK5, G2WP09, N1NY13
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36534.2

    Gene LinkOut

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