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    MRPL17 mitochondrial 54S ribosomal protein YmL17/YmL30 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855469, updated on 28-Oct-2024

    Summary

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    Official Symbol
    MRPL17
    Official Full Name
    mitochondrial 54S ribosomal protein YmL17/YmL30
    Primary source
    SGD:S000005196
    Locus tag
    YNL252C
    See related
    AllianceGenome:SGD:S000005196; FungiDB:YNL252C; VEuPathDB:YNL252C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    mL46; MRPL30
    Summary
    A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL46 (mitochondrial ribosomal protein L46). [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    See MRPL17 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (171441..172286, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Rtc4p Neighboring gene Tex1p Neighboring gene Nrd1 complex RNA-binding subunit Neighboring gene MRX complex DNA-binding subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MrpL35, a mitospecific component of mitoribosomes, plays a key role in cytochrome c oxidase assembly. Box JM, et al. Mol Biol Cell, 2017 Nov 15. PMID 28931599, Free PMC Article
    2. Characterization of the BUD31 gene of Saccharomyces cerevisiae. Masciadri B, et al. Biochem Biophys Res Commun, 2004 Aug 6. PMID 15303280
    3. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Kitakawa M, et al. Eur J Biochem, 1997 Apr 15. PMID 9151978
    4. The yeast protein Mam33 functions in the assembly of the mitochondrial ribosome. Hillman GA, et al. J Biol Chem, 2019 Jun 21. PMID 31053642, Free PMC Article
    5. The DEAD-box helicase Mss116 plays distinct roles in mitochondrial ribogenesis and mRNA-specific translation. De Silva D, et al. Nucleic Acids Res, 2017 Jun 20. PMID 28520979, Free PMC Article

    See all (56) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL17/YmL30
    NP_014147.1
    • Mitochondrial ribosomal protein of the large subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      171441..172286 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183090.1 → NP_014147.1  TPA: mitochondrial 54S ribosomal protein YmL17/YmL30 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014147.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0U1, P36528
      UniProtKB/TrEMBL
      A6ZRJ1, B3LP96, B5VQF7, C7GPA9, C8ZFY5, G2WLL4, N1NYE8
      Conserved Domains (2) summary
      pfam11788
      Location:23 → 150
      MRP-L46; 39S mitochondrial ribosomal protein L46
      cl00447
      Location:153 → 270
      Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36528.2

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