U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RRN11 Rrn11p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854964, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RRN11
    Official Full Name
    Rrn11p
    Primary source
    SGD:S000004507
    Locus tag
    YML043C
    See related
    AllianceGenome:SGD:S000004507; FungiDB:YML043C; VEuPathDB:YML043C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables RNA polymerase I core promoter sequence-specific DNA binding activity and TBP-class protein binding activity. Involved in nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus. Part of RNA polymerase I core factor complex. [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RRN11 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (190244..191767, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene gag protein Neighboring gene gag-pol fusion protein Neighboring gene carnitine O-acetyltransferase CAT2 Neighboring gene Vps71p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I. Lalo D, et al. J Biol Chem, 1996 Aug 30. PMID 8702872
    2. Suppression of oxidative damage by Saccharomyces cerevisiae ATX2, which encodes a manganese-trafficking protein that localizes to Golgi-like vesicles. Lin SJ, et al. Mol Cell Biol, 1996 Nov. PMID 8887660, Free PMC Article
    3. Architecture of the Saccharomyces cerevisiae RNA polymerase I Core Factor complex. Knutson BA, et al. Nat Struct Mol Biol, 2014 Sep. PMID 25132180, Free PMC Article
    4. TATA binding protein can stimulate core-directed transcription by yeast RNA polymerase I. Aprikian P, et al. Mol Cell Biol, 2000 Jul. PMID 10866683, Free PMC Article
    5. A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae. Lin CW, et al. Mol Cell Biol, 1996 Nov. PMID 8887672, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA polymerase I core promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase I core promoter sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase I core promoter sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase I general transcription initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables TBP-class protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables TBP-class protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables TBP-class protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA polymerase I preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleolar large rRNA transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nucleolar large rRNA transcription by RNA polymerase I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in nucleolar large rRNA transcription by RNA polymerase I IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in nucleolar large rRNA transcription by RNA polymerase I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase I promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase I core factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase I core factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Rrn11p
    NP_013669.1
    • Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      190244..191767 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182401.1 → NP_013669.1  TPA: Rrn11p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013669.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZD2, Q04712
      UniProtKB/TrEMBL
      G2WK12, N1NZD2
      Conserved Domains (1) summary
      pfam04090
      Location:173 → 383
      RNA_pol_I_TF; RNA polymerase I specific initiation factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04712.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools