Mogat2 monoacylglycerol O-acyltransferase 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mogat2provided by RGD
Official Full Name: monoacylglycerol O-acyltransferase 2provided by RGD
Primary source: RGD:1598060
See related: EnsemblRapid:ENSRNOG00000027228 AllianceGenome:RGD:1598060
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable 2-acylglycerol O-acyltransferase activity; acetyltransferase activity; and diacylglycerol O-acyltransferase activity. Predicted to be involved in diacylglycerol biosynthetic process; monoacylglycerol biosynthetic process; and triglyceride biosynthetic process. Predicted to act upstream of or within intestinal absorption and lipid metabolic process. Predicted to be located in perinuclear endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human MOGAT2 (monoacylglycerol O-acyltransferase 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Muscle (RPKM 35.1), Lung (RPKM 18.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q32

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (162933964..162957896, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (153521813..153545756, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (164181762..164205222, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 2-acylglycerol O-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 2-acylglycerol O-acyltransferase activity	ISO Inferred from Sequence Orthology more info
enables acetyltransferase activity	ISO Inferred from Sequence Orthology more info
enables diacylglycerol O-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in diacylglycerol biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within diacylglycerol biosynthetic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within intestinal absorption	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within lipid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in monoacylglycerol biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in triglyceride biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within triglyceride biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in triglyceride biosynthetic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in perinuclear endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: 2-acylglycerol O-acyltransferase 2

NP_001102906.2

EC 2.3.1.22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.