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    Zfp612 zinc finger protein 612 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307839, updated on 2-Nov-2024

    Summary

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    Symbol
    Zfp612provided by RGD
    Full Name
    zinc finger protein 612provided by RGD
    Primary source
    RGD:1307197
    See related
    EnsemblRapid:ENSRNOG00000016971 AllianceGenome:RGD:1307197
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp23; Znf23
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF23 (zinc finger protein 23). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 137.0), Adrenal (RPKM 111.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp612 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (54963400..54976888)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (38053953..38071196)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (41556907..41570352, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483643 Neighboring gene carbohydrate sulfotransferase 4 Neighboring gene uncharacterized LOC120098624 Neighboring gene TLE family member 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 23
    Names
    zinc finger protein 23 (KOX 16)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107428.2 → NP_001100898.2  zinc finger protein 23

      See identical proteins and their annotated locations for NP_001100898.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      D3ZLR3
      Conserved Domains (3) summary
      smart00349
      Location:14 → 74
      KRAB; krueppel associated box
      COG5048
      Location:254 → 660
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:454 → 474
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      54963400..54976888
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063278056.1 → XP_063134126.1  zinc finger protein 23 isoform X2

      UniProtKB/TrEMBL
      D3ZLR3

    2. XM_039097754.2 → XP_038953682.1  zinc finger protein 23 isoform X1

      Conserved Domains (3) summary
      smart00349
      Location:14 → 74
      KRAB; krueppel associated box
      COG5048
      Location:254 → 660
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:454 → 474
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_063278055.1 → XP_063134125.1  zinc finger protein 23 isoform X2

      UniProtKB/TrEMBL
      D3ZLR3
      Related
      ENSRNOP00000022757.5, ENSRNOT00000022757.7

    4. XM_006255588.4 → XP_006255650.1  zinc finger protein 23 isoform X1

      See identical proteins and their annotated locations for XP_006255650.1

      UniProtKB/TrEMBL
      D3ZLR3
      Conserved Domains (3) summary
      smart00349
      Location:14 → 74
      KRAB; krueppel associated box
      COG5048
      Location:254 → 660
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:454 → 474
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_039097756.2 → XP_038953684.1  zinc finger protein 23 isoform X2

      UniProtKB/TrEMBL
      D3ZLR3
      Conserved Domains (3) summary
      smart00349
      Location:9 → 69
      KRAB; krueppel associated box
      COG5048
      Location:249 → 655
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_006255589.4 → XP_006255651.1  zinc finger protein 23 isoform X1

      See identical proteins and their annotated locations for XP_006255651.1

      UniProtKB/TrEMBL
      D3ZLR3
      Conserved Domains (3) summary
      smart00349
      Location:14 → 74
      KRAB; krueppel associated box
      COG5048
      Location:254 → 660
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:454 → 474
      ZF_C2H2; C2H2 Zn finger [structural motif]

    7. XM_039097757.2 → XP_038953685.1  zinc finger protein 23 isoform X2

      UniProtKB/TrEMBL
      D3ZLR3
      Conserved Domains (3) summary
      smart00349
      Location:9 → 69
      KRAB; krueppel associated box
      COG5048
      Location:249 → 655
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]

    8. XM_039097758.2 → XP_038953686.1  zinc finger protein 23 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:212 → 618
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412 → 432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 32
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    9. XM_017601293.3 → XP_017456782.1  zinc finger protein 23 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:212 → 618
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:412 → 432
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 32
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    Nucleotide Protein Strain
    Heading Accession and Version

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