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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012102.1 RefSeqGene
- Range
-
5141..89911
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001363744.1 → NP_001350673.1 macrophage scavenger receptor types I and II isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC023396, AK293217, BC063878
- Consensus CDS
-
CCDS87581.1
- UniProtKB/TrEMBL
-
B4DDJ5
- Related
- ENSP00000405453.2, ENST00000445506.6
- Conserved Domains (4) summary
-
- pfam01391
Location:298 → 352
- Collagen; Collagen triple helix repeat (20 copies)
- smart00202
Location:368 → 468
- SR; Scavenger receptor Cys-rich
- pfam03523
Location:139 → 187
- Macscav_rec; Macrophage scavenger receptor
- cl26252
Location:122 → 287
- AAA_13; AAA domain
-
NM_002445.4 → NP_002436.1 macrophage scavenger receptor types I and II isoform type 2
See identical proteins and their annotated locations for NP_002436.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (SR-AII), also known as phSR2, uses two alternative exons and also lacks two downstream exons compared to variant SR-AI. These differences causes an alternate 3' end in the coding region, and has a distinct 3' UTR. It encodes isoform type 2 that is shorter and has a different C-terminus than isoform type 1.
- Source sequence(s)
-
AC023396, D90188
- Consensus CDS
-
CCDS5997.1
- UniProtKB/Swiss-Prot
-
P21757
- Related
- ENSP00000371428.4, ENST00000381998.8
- Conserved Domains (2) summary
-
- pfam01391
Location:280 → 334
- Collagen; Collagen triple helix repeat (20 copies)
- pfam03523
Location:121 → 169
- Macscav_rec; Macrophage scavenger receptor
-
NM_138715.3 → NP_619729.1 macrophage scavenger receptor types I and II isoform type 1
See identical proteins and their annotated locations for NP_619729.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (SR-AI), also known as phSR1, encodes the longest isoform.
- Source sequence(s)
-
AC023396, D90187, DA995755
- Consensus CDS
-
CCDS5995.1
- UniProtKB/Swiss-Prot
- D3DSP3, O60505, P21757, P21759, Q45F10
- Related
- ENSP00000262101.5, ENST00000262101.10
- Conserved Domains (4) summary
-
- pfam01391
Location:280 → 334
- Collagen; Collagen triple helix repeat (20 copies)
- smart00202
Location:350 → 450
- SR; Scavenger receptor Cys-rich
- pfam03523
Location:121 → 169
- Macscav_rec; Macrophage scavenger receptor
- cl26252
Location:104 → 269
- AAA_13; AAA domain
-
NM_138716.3 → NP_619730.1 macrophage scavenger receptor types I and II isoform type 3
See identical proteins and their annotated locations for NP_619730.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (SR-AIII) lacks an exon in the coding region, but maintains the same reading frame, as compared to variant SR-AI. It encodes an isoform type 3 that lacks 63 internal amino acids compared to isoform type 1.
- Source sequence(s)
-
AC023396, D90187, DA995755
- Consensus CDS
-
CCDS5996.1
- UniProtKB/Swiss-Prot
-
P21757
- Related
- ENSP00000262100.3, ENST00000350896.3
- Conserved Domains (4) summary
-
- pfam01391
Location:280 → 334
- Collagen; Collagen triple helix repeat (20 copies)
- smart00202
Location:346 → 387
- SR; Scavenger receptor Cys-rich
- pfam00530
Location:318 → 387
- SRCR; Scavenger receptor cysteine-rich domain
- pfam03523
Location:121 → 169
- Macscav_rec; Macrophage scavenger receptor
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000008.11 Reference GRCh38.p14 Primary Assembly
- Range
-
16107881..16192651 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_024447161.2 → XP_024302929.1 macrophage scavenger receptor types I and II isoform X1
- Conserved Domains (3) summary
-
- pfam01391
Location:298 → 352
- Collagen; Collagen triple helix repeat (20 copies)
- pfam03523
Location:139 → 187
- Macscav_rec; Macrophage scavenger receptor
- cl26252
Location:122 → 287
- AAA_13; AAA domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060932.1 Alternate T2T-CHM13v2.0
- Range
-
16374329..16459913 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054360498.1 → XP_054216473.1 macrophage scavenger receptor types I and II isoform X1