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    ptr-11 SSD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171609, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ptr-11
    Official Full Name
    SSD domain-containing protein
    Primary source
    WormBase:WBGene00004225
    Locus tag
    CELE_F56C11.2
    See related
    AllianceGenome:WB:WBGene00004225
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in molting cycle. Predicted to be located in membrane. Predicted to be active in cytoplasmic vesicle membrane and plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See ptr-11 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    14
    Sequence:
    Chromosome: I; NC_003279.8 (160190..166819, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene NAD(P)H oxidase (H2O2-forming) Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene Dual oxidase 1 Neighboring gene Carboxylic ester hydrolase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GRD-1/PTR-11, the C. elegans hedgehog/patched-like morphogen-receptor pair, modulates developmental rate. Emans SW, et al. Development, 2023 Dec 15. PMID 37982457,
    2. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Kuwabara PE, et al. Genes Dev, 2000 Aug 1. PMID 10921907, Free PMC Article
    3. Identification of innate immunity genes and pathways using a comparative genomics approach. Alper S, et al. Proc Natl Acad Sci U S A, 2008 May 13. PMID 18463287, Free PMC Article
    4. The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans. Zugasti O, et al. Genome Res, 2005 Oct. PMID 16204193, Free PMC Article
    5. Regulation of signaling genes by TGFbeta during entry into dauer diapause in C. elegans. Liu T, et al. BMC Dev Biol, 2004 Sep 20. PMID 15380030, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GRD-1/PTR-11, the C. elegans hedgehog/patched-like morphogen-receptor pair, modulates developmental rate.
      Title: GRD-1/PTR-11, the C. elegans hedgehog/patched-like morphogen-receptor pair, modulates developmental rate.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasmic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SSD domain-containing protein
    NP_001293213.1
    • Confirmed by transcript evidence
    NP_490687.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      160190..166819 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058286.8 → NP_490687.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490687.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44978
      Conserved Domains (1) summary
      cl25655
      Location:35 → 791
      Patched; Patched family

    2. NM_001306284.3 → NP_001293213.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293213.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CLI4
      Conserved Domains (1) summary
      pfam02460
      Location:1 → 640
      Patched; Patched family
    Nucleotide Protein
    Heading Accession and Version

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