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    ZNF699 zinc finger protein 699 [ Homo sapiens (human) ]

    Gene ID: 374879, updated on 23-Nov-2023

    Summary

    Official Symbol
    ZNF699provided by HGNC
    Official Full Name
    zinc finger protein 699provided by HGNC
    Primary source
    HGNC:HGNC:24750
    See related
    Ensembl:ENSG00000196110 MIM:609571; AllianceGenome:HGNC:24750
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    hang; DEGCAGS
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary (RPKM 1.9), endometrium (RPKM 1.5) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ZNF699 in Genome Data Viewer
    Location:
    19p13.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (9291140..9309838, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (9417345..9436045, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9401816..9420514, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily E member 19 pseudogene Neighboring gene olfactory receptor family 7 subfamily H member 1 pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:9406829-9407424 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10037 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13927 Neighboring gene Sharpr-MPRA regulatory region 15409 Neighboring gene ZNF559-ZNF177 readthrough Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13928 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10038 Neighboring gene zinc finger protein 559 Neighboring gene UBXN2A pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ38144, MGC129880, MGC129881

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 699
    Names
    hangover homolog
    hangover, Drosophila, homolog of

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198535.3NP_940937.1  zinc finger protein 699

      See identical proteins and their annotated locations for NP_940937.1

      Status: VALIDATED

      Source sequence(s)
      AC011451, BC109267, BX280105
      Consensus CDS
      CCDS42495.1
      UniProtKB/Swiss-Prot
      Q32M78, Q8N9A1
      Related
      ENSP00000467723.1, ENST00000591998.6
      Conserved Domains (6) summary
      smart00349
      Location:1979
      KRAB; krueppel associated box
      COG5048
      Location:171605
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:477497
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:475497
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:1958
      KRAB; KRAB box
      pfam13465
      Location:545570
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      9291140..9309838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      9417345..9436045 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)