U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from MedGen

    • Showing Current items.

    GCNA germ cell nuclear acidic peptidase [ Homo sapiens (human) ]

    Gene ID: 93953, updated on 17-Sep-2024

    Summary

    Official Symbol
    GCNAprovided by HGNC
    Official Full Name
    germ cell nuclear acidic peptidaseprovided by HGNC
    Primary source
    HGNC:HGNC:15805
    See related
    Ensembl:ENSG00000147174 MIM:300369; AllianceGenome:HGNC:15805
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ACRC; NAAR1; SPGFX4
    Summary
    Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis (RPKM 6.8), adrenal (RPKM 2.2) and 12 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See GCNA in Genome Data Viewer
    Location:
    Xq13.1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (71578437..71613583)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (70011688..70046833)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (70798287..70833433)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chrX:70752005-70753204 Neighboring gene SOCS6 pseudogene 1 Neighboring gene O-linked N-acetylglucosamine (GlcNAc) transferase Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:70798494-70799135 Neighboring gene Sharpr-MPRA regulatory region 14051 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29746 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29745 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29747 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29748 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29749 Neighboring gene Sharpr-MPRA regulatory region 2992 Neighboring gene C-X-C motif chemokine receptor 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29750 Neighboring gene chromosome X open reading frame 49 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29751 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29752

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables SUMO polymer binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein-DNA covalent cross-linking repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in PML body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    germ cell nuclear acidic protein
    Names
    acidic repeat containing
    acidic repeat-containing protein
    germ cell nuclear antigen
    putative nuclear protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_052957.5NP_443189.1  germ cell nuclear acidic protein

      See identical proteins and their annotated locations for NP_443189.1

      Status: VALIDATED

      Source sequence(s)
      AL590763
      Consensus CDS
      CCDS35326.1
      UniProtKB/Swiss-Prot
      B9EG62, Q96QF7
      UniProtKB/TrEMBL
      B3KXM1
      Related
      ENSP00000362800.3, ENST00000373696.8
      Conserved Domains (1) summary
      smart00731
      Location:519677
      SprT; SprT homologues

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      71578437..71613583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      70011688..70046833
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)