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    GPR101 G protein-coupled receptor 101 [ Homo sapiens (human) ]

    Gene ID: 83550, updated on 2-May-2024

    Summary

    Official Symbol
    GPR101provided by HGNC
    Official Full Name
    G protein-coupled receptor 101provided by HGNC
    Primary source
    HGNC:HGNC:14963
    See related
    Ensembl:ENSG00000165370 MIM:300393; AllianceGenome:HGNC:14963
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GPCR6; PAGH2; PITA2
    Summary
    The protein encoded by this gene is an orphan G protein-coupled receptor of unknown function. The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. [provided by RefSeq, Sep 2011]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See GPR101 in Genome Data Viewer
    Location:
    Xq26.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (137023929..137033995, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (135332378..135342444, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (136106088..136116154, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L22 pseudogene 23 Neighboring gene transmembrane 9 superfamily member 5, pseudogene Neighboring gene serine/arginine repetitive matrix 1 pseudogene 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:136113166-136113710 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:136113711-136114254 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21033 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:136162121-136162622 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:136162623-136163122 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:136179005-136179227 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21034 Neighboring gene VISTA enhancer hs755 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:136487294-136487794 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:136509052-136509979 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:136509980-136510906 Neighboring gene Rac family small GTPase 1 pseudogene 4 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chrX:136631085-136631893 Neighboring gene long intergenic non-protein coding RNA 2931

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of receptor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    probable G-protein coupled receptor 101

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016367.2 RefSeqGene

      Range
      5001..15067
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_1000

    mRNA and Protein(s)

    1. NM_054021.2NP_473362.1  probable G-protein coupled receptor 101

      See identical proteins and their annotated locations for NP_473362.1

      Status: VALIDATED

      Source sequence(s)
      AL390879
      Consensus CDS
      CCDS14662.1
      UniProtKB/Swiss-Prot
      Q5JSM8, Q8NG93, Q96P66
      Related
      ENSP00000498972.1, ENST00000651716.2
      Conserved Domains (2) summary
      pfam00001
      Location:48222
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      pfam09309
      Location:243334
      FCP1_C; FCP1, C-terminal

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      137023929..137033995 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      135332378..135342444 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)